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MetabolomicsMetabolic signature of idiopathic inflammatory myopathy
Not available
ORGANISM(S): Homo sapiens 
ST002196 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human muscle tissue in patients with inflammatory myopathies
Molecular profiles of muscle tissue in patients with inflammatory myopathies
ORGANISM(S): Homo sapiens 
2007-09-20 | E-GEOD-281 | biostudies-arrayexpress
TranscriptomicsInflammation-induced acute phase response in skeletal muscle and critical illness myopathy
Objectives: Systemic inflammation is a major risk factor for critical-illness myopathy (CIM) but its pathogenic role in muscle is uncertain. We observed that interleukin 6 (IL-6) and serum amyloid A1 (SAA1) expression was upregulated in muscle of critically ill patients. To test the relevance of the...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-53702 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human muscle specimens from 10 HIBM patients carrying the M712T Persian Jewish founder mutation to investigate hereditary inclusion body myopathy (HIBM)
HIBM is a neuromuscular disorder characterized by adult-onset, slowly progressive distal and proximal muscle weakness. Here, gene expression was measured in muscle specimens from 10 HIBM patients carrying the M712T Persian Jewish founder mutation in GNE and presenting with mild histological changes,...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-12648 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in equine polysaccharide storage myopathy
Standardized muscular biopsies of the dorsal compartment of the gluteus medius muscle were performed in 7 horses suffering from equine polysaccharide storage myopathy (PSSM) and 6 sound Norman Cob horses . Gene expression analysis was performed using an equine oligonucleotide microarray which includ...
ORGANISM(S): Equus caballus 
2009-04-08 | E-GEOD-15572 | biostudies-arrayexpress
ProteomicsMuscle biopsies from human neuromuscular diseases with dystrophic, inflammatory and myopathic pathology reveal common alterations in mitochondrial function
Neuromuscular disorders (NMDs) are clinically and genetically heterogenous and manifest as dystrophic, inflammatory and myopathic pathologies, among others. Our previous study on the cardiotoxin (CTX) mouse model of myodegeneration and inflammation linked muscle pathology with mitochondrial damage a...
ORGANISM(S): Homo sapiens (Human) 
2016-04-04 | PXD002760 | Pride
Proteomics Dystrophy Orbitrap 
MetabolomicsAssociation between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease

Chagas disease causes a cardiac illness characterized by immunoinflammatory reactions leading to myocardial fibrosis and remodeling. The development of Chronic Chagas Cardiomyopathy (CCC) in some patients while others remain asymptomatic is not fully understood, but dysregulated inflammatory resp...

2024-01-11 | MTBLS8390 | MetaboLights
ProteomicsBrachio-Cervical Inflammatory Myopathy: A Distinct Syndrome with Variable Association to Systemic Sclerosis — Insights from Clinical, Histopathological, and Transcriptomic Profiling
Brachio-cervical inflammatory myopathy (BCIM) is a rare and under-characterized subtype of idiopathic inflammatory myopathies (IIM), marked by prominent upper limb and neck muscle involvement. Since its initial description in 2006, few studies have addressed its clinical spectrum or pathogenesis, an...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD070103 | Pride
Inflammatory myopathy B cells Systemic clerosis Myositis 
UnknownHealth-Related Quality of Life (HRQoL) in Idiopathic Inflammatory Myopathy: A Systematic Review.
Not available
S-EPMC4978480 | biostudies-literature
MetabolomicsRBC Balanced Immuno-inflammatory Signatures Identify Advanced Breast Cancer Patients on CDK4/6 Inhibitors at Increased Risk of Progression and Death

Recent studies show red blood cell (RBC) plays an essential role in regulating immunity. Nevertheless, the association of immuno-inflammatory parameters, especially RBC balanced signatures, with survival outcomes and adverse events still require investigation for advanced breast cancer (ABC) pati...

2025-04-15 | MTBLS10792 | MetaboLights
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