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TranscriptomicsAberrantly expressed genes in HaCaT keratinocytes chronically exposed to arsenic trioxide
The purpose of this study is to search for aberrant genes in HaCaT keratinocytes after chronic exposure to arsenic trioxide. The objective of the investigation was to discover the mechanism of arsenic carcinogenicity in human epidermal keratinocytes. We hypothesize that a combined strategy of DNA mi...
ORGANISM(S): Homo sapiens 
2012-04-11 | E-GEOD-37192 | biostudies-arrayexpress
TranscriptomicsPrenatal arsenic exposure and the epigenome: altered gene expression profiles in newborn cord blood
The Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Gómez Palacio, Mexico was recently established to better understand the impacts of prenatal exposure to inorganic arsenic (iAs). In this study, we examined a subset (n = 40) of newborn cord blood samples for microRNA (miRNA) expression...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-48354 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiles of Pancreatic β-Cells and Islets Exposed to Arsenic, Islets (part-II)
Not available
ORGANISM(S): Mus musculus 
ST001314 | MetabolomicsWorkbench
TranscriptomicsPrenatal arsenic exposure and the epigenome: altered miRNA expression profiles in newborn cord blood
The Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort in Gómez Palacio, Mexico was recently established to better understand the impacts of prenatal exposure to inorganic arsenic (iAs). In this study, we examined a subset (n = 40) of newborn cord blood samples for microRNA (miRNA) expression...
ORGANISM(S): Homo sapiens 
2014-01-22 | E-GEOD-48353 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiles of Pancreatic β-Cells and Islets Exposed to Arsenic, part I β-Cells
Not available
ORGANISM(S): Mus musculus 
ST001266 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human U266, MM.1s, KMS11, 8226/S multiple myeloma cell lines treated with arsenic
We used microarrays to examine changes in gene expression in multiple myeloma cell lines following treatment with arsenic trioxide and darinaparsin Experiment Overall Design: Four multiple myeloma cell lines (U266, MM.1s, KMS11, 8226/S) were treated with either arsenic trioxide (ATO) for 6, 24, or 4...
ORGANISM(S): Homo sapiens 
2009-02-01 | E-GEOD-14519 | biostudies-arrayexpress
TranscriptomicsDNA microarray analysis for HepG2 cells exposed to arsenic trioxide
DNA microarray analysis revealed that the genes related to cell cycle regulation were significantly induced at non- and sub-lethal concentrations (i.e., 0.05-6 M-BM-5M), while the common feature of heavy metal toxicity such as oxidative damage and following increase in glutathione, heat shock protei...
ORGANISM(S): Homo sapiens 
2013-07-02 | E-GEOD-48441 | biostudies-arrayexpress
TranscriptomicsRNA-seq in MCF-7 cells which had been exposed to arsenic
In this study, we examined the effect of inorganic arsenic (iAs) on the estrogen response (E2) in MCF-7 cells that are estrogen receptor positive/progesterone receptor positive (ER+/PR+). Understanding the changes in the transcriptomic response after iAs exposure and the retention of such responses...
ORGANISM(S): Homo sapiens 
2020-10-21 | E-MTAB-9498 | biostudies-arrayexpress
TranscriptomicsGene expression responses to chronic low dose arsenite exposure
Arsenic (As) exposure is a significant worldwide environmental health concern. Low dose, chronic arsenic exposure has been associated with higher risk of skin, lung, and bladder cancer, as well as cardiovascular disease and diabetes. While arsenic-induced biological changes play a role in disease p...
ORGANISM(S): Homo sapiens 
2015-05-05 | E-GEOD-60760 | biostudies-arrayexpress
GenomicsImmunomodulation of the prostate tumor microenvironment following inorganic Arsenic exposure
Immunomodulation of the prostate tumor microenvironment following inorganic Arsenic exposure
PRJNA1406262 | ENA
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