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MetabolomicsRhizosphere reprogramming by phosphate slag enhances glutathione-centered redox regulation and root development in tobacco

Background and aims: Phosphate slag, a by-product of phosphorus and steel production, is a potential soil amendment that improves nutrient availability and redox stability. However, how it reshapes the rhizosphere microbiome and metabolism to promote tobacco (Nicotiana tabacum L.) root developmen...

2026-01-16 | MTBLS13273 | MetaboLights
MetabolomicsA homeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism

Cellular senescence affects many physiological and pathological processes and is characterized by durable cell cycle arrest, an inflammatory secretory phenotype and metabolic reprogramming. Here, by using dynamic transcriptome and metabolome profiling in human fibroblasts with different subtypes ...

2024-01-09 | MTBLS7118 | MetaboLights
MetabolomicsA Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency
Both marine phytoplankton and terrestrial plants have to deal with limited bioavailability of the key life nutrient, phosphate. In freshwater algae and plants, a phosphate starvation response gene (psr1) has been characterized, which encodes for a transcription factor that regulates the metabolic re...
2016-02-01 | MTBLS295 | MetaboLights
MetabolomicsInorganic Carbon Limitation in Cells of the Wild Type and Photorespiratory Mutants of the Cyanobacterium Synechocystis sp. Strain PCC 6803
The amount of inorganic carbon represents one of the main environmental factors determining productivity of photoautotrophic organisms. Using the model cyanobacterium Synechocystis sp. PCC 6803, we performed a first metabolome study with cyanobacterial cells shifted from high CO2 (5% in air) into co...
2015-09-14 | MTBLS5 | MetaboLights
ProteomicsEngineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo
To realize a carbon-neutral bioeconomy, the concept of electrobiocatalysis has been developed, in which CO2 is first chemically reduced to formate and subsequently assimilated by enzymatic cascades or engineered microbes. A key step in the assimilation of formate is its reduction into formaldehyde, ...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2023-03-22 | MSV000091532 | MassIVE
TranscriptomicsGenome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe [gene expression data]
Inorganic phosphate is an essential nutrient required by organisms for growth. During phosphate starvation, Saccharomyces cerevisiae activates the phosphate signal transduction (PHO) pathway leading to the expression of the secreted acid phosphatase, PHO5. The fission yeast, Schizosaccharomyces pomb...
ORGANISM(S): Schizosaccharomyces pombe 972h- 
2013-01-02 | E-GEOD-39478 | biostudies-arrayexpress
GenomicsGenome-Wide Characterization of the Phosphate Starvation Response in Schizosaccharomyces pombe [ChIP-Seq data]
Inorganic phosphate is an essential nutrient required by organisms for growth. During phosphate starvation, Saccharomyces cerevisiae activates the phosphate signal transduction (PHO) pathway leading to the expression of the secreted acid phosphatase, PHO5. The fission yeast, Schizosaccharomyces pomb...
ORGANISM(S): Schizosaccharomyces pombe 972h- 
2013-01-02 | E-GEOD-39498 | biostudies-arrayexpress
MetabolomicsGlyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation in Pseudomonas putida

Metabolically versatile Pseudomonas species can assimilate various glycolytic and gluconeogenic substrates. Simultaneous assimilation is known to involve segregating carbons from each substrate type into different metabolic pathways, but the mechanisms that govern this segregation remain unresolv...

2025-11-03 | MTBLS12468 | MetaboLights
TranscriptomicsA conserved two-component signal transduction system controls the response to phosphate starvation in Bifidobacterium breve UCC2003
This work reports on the identification and molecular characterization of a two-component regulatory system (2CRS), encoded by phoRP in Bifidobacterium breve UCC2003, which controls the response to phosphate (Pi) starvation. The response regulator PhoP was shown to bind to the promoter region of pst...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-09-06 | E-GEOD-34983 | biostudies-arrayexpress
ProteomicsFission yeast metabolome dynamics during phosphate starvation and replenishment
Inorganic phosphate is an essential nutrient acquired by cells from their environment and assimilated into myriad intracellular metabolites and macromolecules. Here we characterize the metabolic responses of fission yeast to a 24-h interval of phosphate starvation, during which cells enter a state o...
ORGANISM(S): Schizosaccharomyces Pombe (ncbitaxon:4896) 
2024-12-17 | MSV000096678 | MassIVE
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