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MetabolomicsInositol Pyrophosphates Mediate Chloroplast Lipid Remodeling and Nuclear Gene Repression during High-Light Acclimation in Chlamydomonas reinhardtii
Microalgae are photosynthetic organisms capable of autotrophic growth. Their applicability in multiple industrial fields has been largely studied, thanks to their ability to fixate CO2 into high added value organic products like fatty acids and carotenoids. However, our under-standing of the cellula...
2026-06-09 | MTBLS14720 | MetaboLights
ProteomicsInteraction with IP6K1 supports pyrophosphorylation of substrate proteins by the inositol pyrophosphate 5-IP7
HEK293T cells transiently transfected to express either SFB-tagged GFP or SFB-tagged IP6K1 were lysed in NETN buffer (20 mM Tris-HCl, pH 8.0, 100 mM NaCl, 1 mM EDTA, 0.5% Nonidet P-40) containing protease and phosphatase inhibitor cocktails (Merck), at 4 degree C for 60 min. Cell debris were removed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-20 | MSV000092218 | MassIVE
UnknownStructural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.
Not available
S-EPMC3923263 | biostudies-literature
GenomicsInositol pyrophosphate InsP8 acts as intracellular phosphate signal in Arabidopsis
Inositol pyrophosphate InsP8 acts as intracellular phosphate signal in Arabidopsis
PRJNA523789 | ENA
ProteomicsA GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases
Inositol pyrophosphates are highly phosphorylated nutrient messengers. The final step of their biosynthesis is catalyzed by diphosphoinositol pentakisphosphate kinase (PPIP5K) enzymes, which are conserved among fungi, plants, and animals. PPIP5Ks contain an N-terminal kinase domain that generates th...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-10-07 | PXD056020 | Pride
Inositol pyrophosphate Schizosaccharomyces pombe Histidine acid phosphatase Arabidopsis thaliana. hdx-ms Phytase Saccharomyces cerevisiae Enzyme mechanism Phosphate homeostasis Gaf domain Inositol pyrophosphate phosphatase 
GenomicsInositol pyrophosphate dynamics impact fission yeast phosphate homeostasis via modulation of RNA 3' processing and transcription termination
Inositol pyrophosphate dynamics impact fission yeast phosphate homeostasis via modulation of RNA 3' processing and transcription termination
PRJNA543029 | ENA
UnknownBiochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus.
Not available
S-EPMC10897400 | biostudies-literature
UnknownFluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs.
Not available
S-EPMC7615343 | biostudies-literature
TranscriptomicsInositol pyrophosphate dynamics impact fission yeast phosphate homeostasis via modulation of RNA 3' processing and transcription termination
This RNA-Seq analysis compares gene expression of the Inositol pyrophosphate phosphatase mutant aps1∆ and Inositol pyrophsophate kinase mutant asp1-D333A contrasting to the WT in the fission yeast S. pombe
ORGANISM(S): Schizosaccharomyces pombe 
2019-06-16 | GSE131237 | GEO
UnknownCellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues.
Not available
S-EPMC5076471 | biostudies-literature
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