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TranscriptomicsMiRNA profiling in Rattus norvegicus pancreatic cells: INS-1E cells during infection with Coxsackie B4 virus
This study aims at elucidating how Coxsackie B virus infection perturbs the host's miRNA regulatory pathways that may lead to different pathological events using the miRNA microarray approach. The rat pancreatic cell line - INS-1E, was infected with various preparations of Coxsackie B4 viruses was a...
ORGANISM(S): Rattus norvegicus 
2015-01-01 | E-GEOD-58691 | biostudies-arrayexpress
ProteomicsInteractome of Ca2+-bound secretagogin in INS-1E cells
By using His6-tagged recombinant human secretagogin in the presence of Ca2+ (100 µM), we precipitated putative interacting partners from INS-1E cells and identified their amino acid sequences by mass spectrometry. We detected canonical interacting proteins participating in vesicle-mediated transport...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-06-21 | PXD006544 | Pride
Ins-1e cell line His6-tagged recombinant secretagogin Pull down Protein-protein interactions 
GenomicsIntegrative genomics outlines a biphasic glucose response and a ChREBP-RORγ axis regulating proliferation in β-cells
Glucose is an important regulator of pancreatic β-cell function. In addition to the acute stimulation of insulin secretion, glucose stimulates long-term adaptive changes in gene expression that can either promote or antagonize the proliferative potential and function of β-cells. The glucose-sensin...
ORGANISM(S): Rattus norvegicus 
2016-09-06 | E-GEOD-81628 | biostudies-arrayexpress
UnknownSfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E.
Not available
S-EPMC6438539 | biostudies-literature
UnknownOverexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells.
Not available
S-EPMC6994519 | biostudies-literature
UnknownA possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets.
Not available
S-EPMC3919173 | biostudies-literature
UnknownThe zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells.
Not available
S-EPMC6565745 | biostudies-literature
Genomics
ChIP-seq of Jazf1 in the rat pancreatic beta cell line INS-1E
PRJNA595471 | ENA
TranscriptomicsRat insulin-producing INS-1E exposed to cytokines IL-1β and IFN-γ
In the context of T1 Diabetes, pro-inflammatory cytokines IL-1β and IFN-γ are known to contribute to β-cell apoptosis; The measurement of mRNA expression following β-cell exposure to these cytokines gives a picture of the changes in gene expression characterizing the path to β-cell dysfunction and d...
ORGANISM(S): Rattus norvegicus 
2013-12-19 | E-GEOD-53453 | biostudies-arrayexpress
GenomicsRattus norvegicus
MiRNA profiling in Rattus norvegicus pancreatic cells: INS-1E cells during infection with Coxsackie B4 virus
PRJNA253185 | ENA
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