Insr - OmicsDI

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Unknown (485)
Transcriptomics (462)
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Organisms

Homo sapiens (195)
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Pristionchus pacificus (8)
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synthetic construct (3)
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Organisms

Mus musculus (38)
Homo sapiens (15)
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Repository

biostudies-arrayexpress (434)
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Technology Type

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Instrument Platform

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Publication Date

2015 (152)
2016 (99)
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2013 (40)
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2007 (16)
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2006 (4)
2005 (1)
2003 (1)

CHEBI ID

CHEBI:85753 (3)
CHEBI:85837 (3)
CHEBI:85754 (3)
CHEBI:85752 (3)
CHEBI:85748 (3)
CHEBI:84660 (3)
CHEBI:84661 (3)
CHEBI:85736 (3)
CHEBI:84662 (3)
CHEBI:84665 (3)
CHEBI:85726 (3)
CHEBI:85740 (3)
CHEBI:85876 (3)
CHEBI:85741 (3)
CHEBI:85875 (3)
CHEBI:85729 (3)
CHEBI:85871 (3)
CHEBI:85725 (3)
CHEBI:17202 (3)
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CHEBI:85868 (2)
CHEBI:176402 (2)
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CHEBI:132733 (2)
CHEBI:85747 (2)
CHEBI:72736 (2)
CHEBI:85842 (2)
CHEBI:85843 (2)
CHEBI:85742 (2)
CHEBI:84659 (2)

Metabolite Name

Pantothenic Acid (3)
Glycerophosphocholine (3)
13Z-Docosenamide (2)
Geranylcitronellol (2)
2,5-Dimethylbenzaldehyde (2)
(S)-Oleuropeic acid (2)
LysoPE(0:0/20:5(5Z,8Z,11Z,14Z,17Z)) (2)
LysoPE(20:4(8Z,11Z,14Z,17Z)/0:0) (2)
Linoleamide (2)
LysoPE(0:0/18:3(6Z,9Z,12Z)) (2)
UTP (2)
UDP (2)
Pipecolic Acid (2)
IMP (2)
CTP (2)
ATP (2)
Netilmicin (2)
Propionylcarnitine (2)
Sphingosine (2)
CDP (2)
KAPA (2)
ADP (2)
NADP (2)
NAD (2)
Phytosphingosine (2)
Phosphocholine (2)
Acetylcarnitine (2)
Indole (2)
Methionine sulfoxide (2)
Choline (2)

First Public Date

2026 (20)
2021 (9)
2025 (8)
2016 (6)
2014 (5)
2024 (4)
2020 (4)
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2018 (3)
2013 (3)
2022 (2)
2019 (2)
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Study type

Transcription profiling by array (230)
RNA-seq of coding RNA (88)
RNA-seq of coding RNA from single cells (29)
ChIP-seq (17)
ChIP-chip by tiling array (10)
RNA-seq of non coding RNA (8)
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CUT&RUN (5)
Human - Single-cell sequencing (4)
Baseline (3)
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Cell line - Single-cell sequencing (2)
Unknown experiment type (2)
Differential (2)
Cell line - High-throughput sequencing (2)
Transcription profiling by RT-PCR (2)
ATAC-seq (2)
Methylation profiling by array (2)
Animal - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
Plant - High-throughput sequencing (1)
Trajectory (1)
RNAi profiling by array (1)
ChIP-chip by array (1)
DNA-seq (1)
Proteomic profiling by array (1)

Release Date

2015 (74)
2022 (72)
2025 (58)
2016 (56)
2012 (56)
2021 (55)
2020 (52)
2014 (51)
2023 (49)
2013 (47)
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2011 (46)
2019 (45)
2017 (45)
2010 (45)
2018 (37)
2009 (21)
2007 (18)
2008 (17)
2026 (16)
2006 (6)
2005 (3)
2003 (2)
1999 (1)

Lab affiliation

Emmy-Noether Research Group Cellular Proteomics and Metabolic Signaling Institute for Diabetes and Obesity Helmholtz Diabetes Center Germany (1)
Institute for Diabetes and Obesity (IDO),Helmholtz Zentrum München (1)
Laboratory of Physiology and Toxicology of Reproduction, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków, Poland (1)
Dept. of Physiology, University of Toronto, Toronto, ON, Canada Dept. of Medicine, University of Toronto, Toronto, ON, Canada (1)
EMBL Australia, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia. School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia (1)
Newcastle University Translational and Clinical Research Institute (1)
Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (1)
Mass Spectrometry of Biopolymers, Institute of Organic Chemisty and Biochemistry of the CAS, Czech Republic (1)
1¬ MRM Proteomics Inc, Montreal, Quebec, Canada 2 Segal Cancer Proteomics Centre, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada 3 Gerald Bronfman Department of Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada (1)
State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China (1)
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland 21205 USA (1)
The University of Sydney (1)

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Brain microvascular endothelial cells: INSR KD

The insulin receptor (INSR) mediates insulin signaling to modulate cellular functions. Although INSR is expressed at the blood-brain barrier (BBB), its role in the modulation of BBB function is poorly understood. Therefore, in this study, we aimed to analyze the effect of INSR knockdown on the expre...

ORGANISM(S): Homo Sapiens (human)

2021-12-25 | PXD027326 | JPOST Repository

Effect of insulin receptor knockdown on the proteome and secretome of CYLD cutaneous syndrome primary keratinocytes

CYLD cutaneous syndrome (CCS) is a rare genetic disorder characterized by multiple skin appendage tumors. This study investigated the impact of insulin receptor (INSR) knockdown on the cellular proteome and secretome of CCS primary keratinocytes. Three biological replicates each of control and INSR ...

ORGANISM(S): Homo sapiens (Human)

2026-09-28 | PXD071326 | Pride

Keratinocytes insr cyld

Serge Nef

we performed the analysis of SOX9-GFP+ cells purified from mouse embryonic testis at embryonic day E17.5 and Postnatal day 5 and analyzed the effect of the deletion of the Insulin receptor (InsR) and Igf1 receptor (Igf1R) by comparing double mutant and control SOX9+ Sertoli cells

ORGANISM(S): Mus musculus

2013-03-09 | E-MTAB-1192 | biostudies-arrayexpress

mRNA profiling after knockdown of Circular RNA-INSR

PRJNA818305 | ENA

Gene expression data from mouse colon. AOM+DSS induced colitis. INSR fl/fl mice or villin-CRE INSR-/- mice

PRJNA449720 | ENA

A Pathobiological Role of the Insulin Receptor in CLL.

Purpose: The chromosomal deletion 11q affects biology and clinical outcome in CLL but del11q-deregulated genes remain incompletely characterized. Results: We have identified differential expression of the insulin receptor (INSR) in CLL, including high-level INSR expression in the majority of CLL wi...

ORGANISM(S): Homo sapiens

2011-05-05 | E-GEOD-26526 | biostudies-arrayexpress

mRNA profiling after knockdown of Circular RNA-INSR

The recent advances in anti-cancer treatments have led to a steady increase in the number of cancer survivors, paradoxically also enhancing the number of HF patients who suffer from the undesired cardiotoxic side effects of these anti-tumor treatments. Therapeutic options to reduce or reverse chemot...

ORGANISM(S): Mus musculus

2022-10-01 | GSE199081 | GEO

Alteration of gene expressions in RCC cell lines co-cultured with HGECs with down-regulated INSR

PRJNA962146 | ENA

InsR/FoxO1 signaling curtails hypothalamic POMC neuron number.

Not available

S-EPMC3271107 | biostudies-literature

Hyperinsulinemia acts via acinar INSR to drive obesity-associated PDAC initiation by promoting digestive enzyme production and inflammation

PRJNA952643 | ENA