Ferroptosis, an iron-dependent form of nonapoptotic cell death mediated by lipid peroxidation, has been implicated in the pathogenesis of multiple diseases. Subcellular organelles play pivotal roles in the regulation of ferroptosis, but the mechanisms underlying the contributions of the mitochond...

Microglia, the brain’s primary resident immune cells, can assume various phenotypes with diverse functional outcomes on brain homeostasis. In Alzheimer’s disease (AD), where microglia are a leading causal cell type, the identity of microglia subsets that drive neurodegeneration remains unresolved...

Untargeted metabolomic profiling of Lavandula angustifolia under progressive heat stress conditionsate.

Cell size and the cell cycle are intrinsically coupled and abnormal increases in cell size are associated with senescence and permanent cell cycle arrest. The mechanism by which overgrowth primes cells to withdraw from the cell cycle remains unknown. We investigate this here using CDK4/6 inhibito...

Telenomus remus, an egg parasitoid capable of penetrating multi-layered egg masses, has emerged as a promising candidate for the biological control of Spodoptera frugiperda. Nevertheless, our prior investigations have uncovered that its limited cold tolerance represents a critical bottleneck in m...

Connecting the characterisation of juvenile (pre-anthesis) plant stress responses undertaken in controlled environments to field agronomic performance is a challenge. The oilseed crop Camelina sativa (camelina), with its innate resilience and plasticity, presents an opportunity to understand both...