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TranscriptomicsCre-mediated deletion of b1 integrin in pancreatic b-cells
In this study, we investigated the function of beta integrins in developing islet beta-cells by targeting the deletion of exon 3 of the B1 integrin gene using a Cre-lox approach. Our results demonstrate that this class of integrin receptors is critically important for proper beta cell expansion duri...
ORGANISM(S): Mus musculus 
2013-07-31 | E-MEXP-3736 | biostudies-arrayexpress
TranscriptomicsGene expression in b1-integrin wild-type and knockout mouse heart
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14411 | biostudies-arrayexpress
Genomicsb1-integrin regulates marginal zone B cell differentiation
b1-integrin regulates marginal zone B cell differentiation
PRJNA881272 | ENA
TranscriptomicsThe effect of aneuploidy on gene expression
Analysis of the gene expression changes observed in aneuploid b1 integrin YYFF MEFs generated as a result of repeated cytokinesis failure compared to tetraploid wild-type MEFs or tetraploid b1YYFF integrin MEFs. The results reveal aneuploidy-specific gene expression changes, both up-and downregulate...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-23729 | biostudies-arrayexpress
Genomicsb1 integrin regulates epithelial proliferation and cell shape during alveolar repair
b1 integrin regulates epithelial proliferation and cell shape during alveolar repair
PRJNA847995 | ENA
TranscriptomicsGene expression in mouse heart
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14414 | biostudies-arrayexpress
Transcriptomicsb1-integrin regulates marginal zone B cell differentiation
Integrin b1-deficient mice have a defect in the differentiation of MZ B cells and plasma cells.We performed a genome-wide transcriptome analysis of ex vivo-sorted Fo B, transitional B and MZ B cells of in Integrin b1 KO and Integrin b1 WT mice. We also performed invitro culture of CD93+ (AA4.1+) tra...
ORGANISM(S): Mus musculus 
2022-09-19 | GSE213512 | GEO
GenomicsIntegrin b1 acetylation-induced transcriptomic reprograming of mouse embryonic endothelial cells and functions
Integrin b1 acetylation-induced transcriptomic reprograming of mouse embryonic endothelial cells and functions
PRJNA997375 | ENA
Transcriptomicsb1 integrin regulates epithelial proliferation and cell shape during alveolar repair
Integrins are extracellular matrix receptors comprised of an a and b subunit that connect and mediate signaling between cells and the surrounding matrix. In organogenesis of epithelial tissues, the b1 integrin subunit regulates essential epithelial cell functions, but the role of b1 integrin in epit...
ORGANISM(S): Mus musculus 
2023-06-10 | GSE205882 | GEO
TranscriptomicsGene expression in mouse embyonic cardiomyocytes, fibroblasts and adult cardiac fibroblasts
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14412 | biostudies-arrayexpress
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