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TranscriptomicsTranscription profiling of human MDA-MB-435 breast carcinoma cell line transfected with the integrin beta4 subunit revealsIntegrin alpha6-beta4 control the expression of genes associated with cell motility, invasion and metastasis
The objective of this study was to determine the gene expression changes mediated by the alpha6beta4 integrin using MDA-MB-435 breast carcinoma cell line under normal culturing conditions (10% FCS in DMEM). Experiment Overall Design: Comparison of clones of MDA-MB-435 cells transfected with the inte...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-11466 | biostudies-arrayexpress
TranscriptomicsMulcom: a multiple comparison statistical test for microarray data in Bioconductor (Affymetrix)
Background Many microarray experiments search for genes with differential expression between a common “reference” group and multiple test groups, like in the case of time-course designs or of various treatments versus a control condition. In such cases, currently employed statistical approaches base...
ORGANISM(S): Homo sapiens 
2011-08-09 | E-GEOD-26732 | biostudies-arrayexpress
TranscriptomicsMulcom: a multiple comparison statistical test for microarray data in Bioconductor (Illumina)
Background Many microarray experiments search for genes with differential expression between a common “reference” group and multiple test groups, like in the case of time-course designs or of various treatments versus a control condition. In such cases, currently employed statistical approaches base...
ORGANISM(S): Homo sapiens 
2011-08-09 | E-GEOD-26735 | biostudies-arrayexpress
UnknownBeta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth.
Not available
S-EPMC2064708 | biostudies-literature
TranscriptomicsHigh throughput quantitative whole transcriptome analysis of CC10- B4+ and Krt5-CreERT2 - labeled distal lung cells
We used microfluidic single cell RNA-seq on adult isolated CC10-CreERT2 (negative) integrin beta4(pos) cells lung epithelial cells in order to determine the transcriptional profile of this putative progenitor population. CC10-CreERT2 / tdTomato (negative) integrin beta4(pos) cells were isolated by F...
ORGANISM(S): Mus musculus 
2014-11-17 | E-GEOD-61300 | biostudies-arrayexpress
UnknownThe human papillomavirus type 8 E2 protein suppresses beta4-integrin expression in primary human keratinocytes.
Not available
S-EPMC516394 | biostudies-literature
ProteomicsIntegrin beta4 positive versus integrin beta4 negative human keratinocytes
Proteomics analysis of sorted human basal and suprabasal keratinocytes to confirm the distinct protein expression in the sorted cell populations.
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD034543 | Pride
Human epidermis Stem cells Integrin beta4 
UnknownHuman papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an activator of the beta4-integrin gene in human keratinocytes.
Not available
S-EPMC2812352 | biostudies-literature
UnknownEpidermolysis bullosa with pyloric atresia: novel mutations in the beta4 integrin gene (ITGB4).
Not available
S-EPMC1858138 | biostudies-literature
UnknownThe beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly.
Not available
S-EPMC2148184 | biostudies-literature
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