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Delineating the extracellular interaction network of the cell surface proteotype (the surfaceome) is fundamental to understanding cellular signaling function in health and disease. Here, we developed LUX-MS, an optoproteomic technology that enables the spatiotemporal and proteome-wide study of surfa...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) Listeria monocytogenes serotype 4b Listeria phage A500 Escherichia coli 
2021-06-14 | PXD020481 | Pride
DIISCO: A Bayesian framework for inferring dynamic intercellular interactions from time-series single-cell data
Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions
Metastasis is a major cause of mortality, and remains a final frontier in the search for a cure for cancer. While there has been much research on the ‘seed’ (metastatic tumor cells) and the ‘soil’ (colonized host tissue), interactions between metastatic cancer cells and stromal endothelial cells, wh...
ORGANISM(S): Homo sapiens 
Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions [xenium_cohort3]
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