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GenomicsInterferon-induced transmembrane protein 1 (IFITM1) inhibits Varicella-Zoster Virus Replication
Interferon-induced transmembrane protein 1 (IFITM1) inhibits Varicella-Zoster Virus Replication
PRJNA693278 | ENA
TranscriptomicsEffects of IFITM1 knockdown in colorectal cancer
Interferon-induced transmembrane protein 1 (IFITM1) is one of the three members of the interferon-induced transmembrane family and has recently been identified as a new molecular marker in human colorectal cancer. However, its functional roles in colorectal cancer are still elusive. In this study, w...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-20923 | biostudies-arrayexpress
TranscriptomicsInterferon-induced transmembrane protein 1 (IFITM1) inhibits Varicella-Zoster Virus Replication
Hosts have evolved numerous mechanisms to prevent primary viral infections. Interferon signaling is an important host defense mechanism against primary infection. Interferon gamma (IFN-γ) is a potent cytokine produced following primary varicella-zoster virus (VZV) infection. Furthermore, VZV reactiv...
ORGANISM(S): Homo sapiens 
2021-01-20 | GSE165112 | GEO
TranscriptomicsThe interferon induced transmembrane protein 1 (Ifitm1): detailed analysis on its assumed functions
Several functions have been suggested for the interferon induced transmembrane protein 1 (Iftitm1) gene in mammals. Originally it was identified as a member of a gene family that is highly inducible by type I and type II inteferons. Based on its expression during primordial germ CELl (PGC) specifica...
ORGANISM(S): Mus musculus 
2012-08-06 | GSE24744 | GEO
ProteomicsSRSF1 as a novel interacting partner for IFITM1/3 unravels the emergent role of IFITM1/3 mediating protein expression
IFITM proteins play a role in cancer cell progression through undefined mechanisms. Recent data demonstrated that interferon induced transmembrane 1 and 3 (IFITM1/3) proteins are required for the interferon gamma (IFNγ) stimulated synthesis of a subset of IFN-stimulated proteins; including human leu...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD030540 | Pride
Mass spectrometry Interferon Ribosome Isoform of serine and arginine rich splicing factor 1 Crispr/cas Mrna Interferon induced transmembrane 1 and 3 
UnknownInterferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer.
Not available
S-EPMC5349895 | biostudies-literature
UnknownInterferon-Induced Transmembrane Protein 1 (IFITM1) Promotes Distant Metastasis of Small Cell Lung Cancer.
Not available
S-EPMC7404048 | biostudies-literature
GenomicsMus musculus
The interferon induced transmembrane protein 1 (Ifitm1): detailed analysis on its assumed functions
PRJNA132139 | ENA
ProteomicsGenetic ablation of ifitm1 and ifitm3 attenuates IFN- mediated induction of ISG15 and MHC class I molecules
Interferon-induced transmembrane protein (IFITM1) plays a dual role in restriction of RNA viruses and in metastatic cancer cell growth. The signal transduction events that are orchestrated by IFITM1 are not well defined. We set out to identify IFITM1 interacting proteins to begin to define its mecha...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD007562 | Pride
Human Cancer Swath Silac Cell lines Ifn Lc-ms/ms 
ProteomicsImmune surveillance of brain metastatic cancer cells is mediated by IFITM1 (The coimmunoprecipitated proteins associated with the endogenous membrane IFITM1 of H1299 cells after IFNγ stimulation)
To examine the molecular basis of IFITM1 function, we performed a coimmunoprecipitation (co-IP) assay of cell membrane proteins followed by mass spectrometry analysis.
ORGANISM(S): Homo sapiens (Human) 
2023-02-17 | PXD038130 | Pride
Non-small cell lung cancer Interferon-induced transmembrane protein 1 (ifitm1) Brain metastatic colonization In vivo pooled genome-wide loss-of-function genetic screen 
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