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ProteomicsDysregulated neutrophil response drives lethality during Citrobacter rodentium infection in interleukin-22 deficient mice
Citrobacter rodentium (CR) is a murine enteric pathogen widely used to model attaching and effacing bacterial disease caused by enteropathogenic and enterohaemorrhagic Escherichia coli. Infection induces colonic epithelial damage and inflammation that resolves in resistant mice but results in severe...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-08 | PXD074250 | Pride
Rodentium infection Mice Citrobacter Interleukin-22 deficient 
GenomicsGene expression profiles in the ileal and colonic epithelial cells from Interleukin (IL)-23-deficient mice and IL-22-deficient mice
Gene expression profiles in the ileal and colonic epithelial cells from Interleukin (IL)-23-deficient mice and IL-22-deficient mice
PRJNA990813 | ENA
TranscriptomicsDOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCs
Retinoic-acid receptor-related orphan receptor-γt-positive (RORγt+) innate lymphoid cells (ILCs) produce interleukin (IL)-22 and IL-17, which are critical for protective immunity against enteric pathogens. The molecular mechanism underlying the development and survival of RORγt+ ILCs is not thorough...
ORGANISM(S): Mus musculus 
2014-06-25 | E-GEOD-58765 | biostudies-arrayexpress
TranscriptomicsIdentification of IL-21-induced STAT3 dependent genes in human B cells
IL-21 induces B cell activation, and differentiation into antibody-secreting plasmablasts in vitro. This process is abolished by loss-of function mutations in STAT3 We used microarrays to identify genes that are induced by IL-21 in a STAT3-dependent manner Sort-purified naïve B cells from four heal...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-51587 | biostudies-arrayexpress
GenomicsOryzias latipes strain:Cab
Transcriptomic analysis of interleukin 22 deficient medaka against DSS exposure
PRJDB11189 | ENA
UnknownTristetraprolin regulation of interleukin-22 production.
Not available
S-EPMC4613560 | biostudies-literature
UnknownInterleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation.
Not available
S-EPMC2149911 | biostudies-literature
GenomicsThe interleukin 22–oncostatin M axis promotes intestinal inflammation and tumorigenesis [Colon_Tissue_BulkRNA-seq]
The interleukin 22–oncostatin M axis promotes intestinal inflammation and tumorigenesis [Colon_Tissue_BulkRNA-seq]
PRJNA1122159 | ENA
UnknownInterleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.
Not available
S-EPMC4720437 | biostudies-literature
UnknownAn Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis.
Not available
S-EPMC6257980 | biostudies-literature
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