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PHF6 regulates stress susceptibility in the pituitary intermediate lobe [RNA-seq]
Obesity and its co-morbidities, such as diabetes and hypertension, can significantly reduce a person’s quality of life and place huge pressure on healthcare resources. When we eat a meal our gut and brain release hormones to control the amount of food and fluid we ingest to prevent overeating. One o...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-03-02 | PXD037495 | Pride
Obesity and its co-morbidities, such as diabetes and hypertension, can significantly reduce a person’s quality of life and place huge pressure on healthcare resources. When we eat a meal our gut and brain release hormones to control the amount of food and fluid we ingest to prevent overeating. One o...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-06-26 | PXD068252 | Pride
PHF6 regulates stress susceptibility in the pituitary intermediate lobe [CUT&Tag]
To investigate the molecular mechanisms associated with initial dose-related events that are linked to the development of liver tumours: liver growth; cell proliferation; changes in histopathology such as hypertrophy Experiment Overall Design: We selected dose levels of phenobarbital to give a carci...
ORGANISM(S): Rattus norvegicus 
Background: Survival and function of insulin-secreting pancreatic β-cells are markedly altered by changes in nutrient availability. In vitro, culture in 10 rather than 2mM glucose improves rodent β-cell survival and function whereas glucose concentrations above 10mM are deleterious. Aim-Method: T...
ORGANISM(S): Rattus norvegicus 
A mouse model of asthma mimicking acute or chronic asthma disease was used to select genes undergoing a modulation in both acute and chronic conditions. Mice were exposed to ovalbumin during 1, 5 and 10 weeks (short, intermediate and long term model (ST, IT, LT)) and gene expression in the lung was ...
ORGANISM(S): Mus musculus 
Tailless (TLX) terminates the neural stem cell temporal cascade in both the optic lobe and central brain
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