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ProteomicsIleal proteomic changes associated with IL-25-mediated resistance against intestinal trematode infections
Previous studies of our group have shown that IL-25 is essential for the resistance to E. caproni infections and the susceptibility of mice relies on the inability of this host species to produce IL-25 in response to infection (14-15). Susceptibility of mice to primary E. caproni infection was assoc...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD019477 | Pride
Intestine Proteomics Intestinal helminths Echinostoma caproni Trematoda Interleukin-25 
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of the mouse intestinal mucosa to infection by the parasitic nematode Trichuris muris
This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ The human-infective whipworm Trichuris trichiura i...
ORGANISM(S): Mus musculus 
2013-05-07 | E-ERAD-181 | biostudies-arrayexpress
TranscriptomicsATAC-sequencing mice small intestinal epithelium with intestinal epithelium specific LSD1 knock out compared to wild type
To study the epigenetic regulation of intestinal epithelium we focus on the role of chromatin modulators. Lysine-specific histone demethylase 1a (KDM1A, LSD1) is one of the enzymes that can erase the H3K4me1/2 mark. To assess the role of LSD1 in intestinal epithelium we studied wild type (WT) (Villi...
ORGANISM(S): Mus musculus 
2021-03-23 | E-MTAB-8718 | biostudies-arrayexpress
TranscriptomicsRNAseq of small intestinal epithelium extracted from mice infected with Nippostrongylus brasiliensis
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. Here we sequenced the small intestinal epithelium from mice infected with Nippostrongylus brasiliens...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9183 | biostudies-arrayexpress
UnknownHelminths as an alternative therapy for intestinal diseases.
Not available
S-EPMC5597493 | biostudies-literature
UnknownThe Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.
Not available
S-EPMC4658337 | biostudies-literature
TranscriptomicsRNAseq of colon intestinal epithelium extracted from mice infected with Citrobacter rodentium
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. Here we sequenced the colon intestinal epithelium from mice infected with Citrobacter rodentium to d...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9184 | biostudies-arrayexpress
GenomicsLoss of Elp3 impairs the immune response to helminths by blocking intestinal tuft cell differentiation
Loss of Elp3 impairs the immune response to helminths by blocking intestinal tuft cell differentiation
PRJNA1009008 | ENA
UnknownMolecular detection of intestinal helminths and protozoa among young children in Dosso Region, Niger.
Not available
S-EPMC7468184 | biostudies-literature
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