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MetabolomicsLipid Profiles of Human Brain Tumors Obtained by High-Resolution Negative Mode Ambient Mass Spectrometry

Alterations in cell metabolism, including changes in lipid composition occurring during malignancy, are well characterized for various tumor types. However, a significant part of studies that deal with brain tumors have been performed using cell cultures and animal models. Here, we present a data...

2021-11-18 | MTBLS1558 | MetaboLights
MetabolomicsMetabolic differences between primary and brain metastatic breast tumors revealed by in vivo [U-¹³C]-glucose infusion in mice

Metastatic breast tumors must adapt to the metabolic constraints of their target tissues. To understand how tumor metabolism varies across sites, we compared glucose utilization in primary mammary fat pad (MFP) tumors and brain metastases derived from the breast cancer cell line MDA-MB-231. Tumor...

2025-12-30 | MTBLS13152 | MetaboLights
TranscriptomicsGenotyping and analysis of chromosome copy number variation (CNV) from pediatric primary intracranial germ cell tumor
Intracranial pediatric germ cell tumors (GCTs) have different histological differentiations, prognosis and clinical behaviors. Prognosis of patients with germinoma and mature teratoma is good, while patients with other types of GCTs, termed as nongerminomatous malignant germ cell tumors (NGMGCTs), r...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-19349 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression data from pediatric primary intracranial germ cell tumor
Intracranial pediatric germ cell tumors (GCTs) have different histological differentiations, prognosis and clinical behaviors. Prognosis of patients with germinoma and mature teratoma is good, while patients with other types of GCTs, termed as nongerminomatous malignant germ cell tumors (NGMGCTs), r...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-19347 | biostudies-arrayexpress
GenomicsEpigenome analysis of intracranial mesenchymal tumors with FET-CREB fusions
Epigenome analysis of intracranial mesenchymal tumors with FET-CREB fusions
PRJNA692742 | ENA
TranscriptomicsTranscription profiling by array of human tumor cells with stem-like properties isolated from pediatric brain tumors
Background
Primitive brain tumors are the first cause of cancer-related death in children. Tumor cells with stem-like properties (TSCs), thought to account for tumorigenesis and therapeutic resistance, have been isolated from high-grade gliomas in adults. Whether TSCs are a common component of pe...
ORGANISM(S): Homo sapiens 
2011-09-07 | E-MEXP-2910 | biostudies-arrayexpress
ProteomicsHuman intracranial tumors LC-MS/MS
We found the reality that each Coomassie blue-stained 2D gel spot contained lots of protein species in analysis of in tissue proteome.
ORGANISM(S): Homo sapiens (Human) 
2017-12-11 | PXD004930 | Pride
Human Lc-ms/ms Intracranial tumors 2d-gel 
TranscriptomicsCopy number alterations of intracranial tumors
Affymetrix OncoScan data from primary and metastatic intracranial lesions collected for the validation of our intraoperative brain tumor classification with nanopore sequencing. All samples were processed from FFPE by our clinical lab using the standard protocol for clinical samples.
ORGANISM(S): Homo sapiens 
2024-12-17 | E-MTAB-14700 | biostudies-arrayexpress
TranscriptomicsArray-CGH in human glial brain tumors
Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Characterization of DNA copy number changes in 54 glial brain tumors using a cDNA microarray-based comparative genomic hybridization method. Tumors: 54 fresh-frozen glioma specimens subjected to sta...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-1991 | biostudies-arrayexpress
TranscriptomicsAn RNAi Screen Identifies TRRAP as a Regulator of Brain Tumor-Initiating Cell Differentiation
Glioblastoma multiforme is the most common and most aggressive type of primary brain tumor. The brain-infiltrative character of glioblastoma makes complete surgical removal of the tumor impossible and neither radiation nor current chemotherapy provide cure. Recent evidence shows that glioblastoma mu...
ORGANISM(S): Homo sapiens 
2011-03-14 | E-GEOD-27931 | biostudies-arrayexpress
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