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7q11.23 CNV alters ribosomal biogenesis, mTOR and neuronal intrinsic excitability [ribosome footprinting]
7q11.23 CNV alters ribosomal biogenesis, mTOR and neuronal intrinsic excitability [RNA-seq]
7q11.23 CNV alters ribosomal biogenesis, mTOR and neuronal intrinsic excitability
Layer V pyramidal neurons, particularly pyramidal tract (PT) neurons, are essential for cortical output. Genetic studies have linked ITGB3, the gene encoding the cell-adhesion molecule β3 integrin, to autism spectrum disorder (ASD), yet its role in brain function remains poorly understood. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-13 | PXD056477 | Pride
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