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MetabolomicsInulin gel-mediated delivery of Clostridium butyricum spores protects against acute kidney injury via regulation of ER-mitochondria contacts
Acute kidney injury (AKI) progression is closely associated with gut microbiota dysbiosis. However, the detailed mechanism remains unclear. In this study, we found that patients with AKI had decreased beneficial bacteria and reduced butyric acid levels in the intestine. Furthermore, butyrate allevia...
2026-09-17 | MTBLS15607 | MetaboLights
TranscriptomicsDifferential gene expression in Roseburia inulinivorans grown on inulin and starch
Roseburia inulinivorans is a recently identified motile representative of the Firmicutes that contributes to butyrate formation from a variety of dietary polysaccharide substrates in the human large intestine. Microarray analysis was used here to investigate substrate-driven gene expression changes ...
ORGANISM(S): Roseburia inulinivorans DSM 16841 
2010-07-24 | E-GEOD-22245 | biostudies-arrayexpress
ProteomicsPotential anti-inflammatory effect of inulin in an inflammatory cell model (mouse macrophages with LPS)
A potential anti-inflammatory effect of inulin, a fructan found in thousands of plant species, has been described. In this study we look at the effect of inulin, at the proteome level, in a murine cellular model of inflammation. Our interest is focused on describing the molecular mechanisms involved...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD032759 | Pride
Inulin  anti-inflammatory effect  diapasef  dia-nn  library-free 
GenomicsPrebiotic inulin-type fructans induce specific changes in the human gut microbiota
ObjectiveContrary to the long-standing prerequisite of inducing selective (i.e. bifidogenic) effects, recent findings suggest that prebiotic interventions lead to ecosystem-wide microbiota shifts. Yet, a comprehensive characterization of this process is still lacking. Here, we apply 16S rDNA microbi...
EGAS00001002173 | EGA
ProteomicsAn integrative multi-omics approach to characterize prebiotic inulin effects on Faecalibacterium prausnitzii
Faecalibacterium prausnitzii, a major commensal bacterium in the human gut, is well known for its anti-inflammatory effects, which improve host intestinal health. Although several studies have reported that inulin, a well-known prebiotic, increases the abundance of F. prausnitzii in the intestine, t...
ORGANISM(S): Faecalibacterium prausnitzii A2-165 Bacteria 
2022-04-04 | PXD030078 | Pride
Prebiotics Pts transporter Beta-fructosidase Abc transporter Faecalibacterium prausnitzii Amylosucrase Inulin Lc-ms/ms 
Genomicsmicrobiota response to inulin
microbiota response to inulin
PRJEB73867 | ENA
Genomicsresponse dynamics of intestinal microbiota to inulin
response dynamics of intestinal microbiota to inulin
PRJEB76647 | ENA
Genomics3FL and Inulin with short and long
3FL and Inulin with short and long
PRJEB113407 | ENA
ProteomicsHIF-1 ATTENUATES THE PROLIFERATIVE EFFECT OF INULIN-DIET THROUGH REWIRING OF METABOLISM
A striking example of the intricate interplay between diet, microbiota, and host is the effect of inulin, a dietary fiber, on the intestinal epithelium. Ingestion of inulin triggers a wide range of epithelial effects in the colon, such as enhanced proliferation, increased production of mucus and ant...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-22 | PXD059757 | Pride
Metabolism Oxidative phosphorylation Hypoxia Dietary fiber Microbiota Intestinal stem cells 
Genomicsceae09f4-f021-444d-b025-bee14880fa30 - samples
16S rDNA amplicon sequencing of 196 human fecal samples of an Inulin cross-over trial in healthy, mildly constipated individuals.
EGAD00001004956 | EGA
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