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ProteomicsProteomic analysis of bronchoalveolar lavage fluid during invasive pulmonary aspergillosis in mice and humans
Comprehensive proteomic analysis of the protein expression landscape of bronchoalveolar lavage fluid during invasive pulmonary aspergillosis in murine and human samples. 38 murine BALF samples (10 Aspergillus fumigatus infected mice without immunosuppression and without invasive pulmonary aspergillo...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-10-14 | PXD016664 | Pride
Bal fluid Proteomics Bronchoalveolar lavage Aspergillus fumigatus Invasive aspergillosis 
ModelsEwald2021 - Innate immune response during invasive aspergillosis by dynamic optimization
Aspergillus fumigatus is an important human fungal pathogen and its conidia are constantly inhaled by humans. In immunocompromised individuals, conidia can grow out as hyphae that damage lung epithelium. The resulting invasive aspergillosis is associated with devastating mortality rates. Since infec...
2021-11-24 | MODEL2105110001 | BioModels
Not Peer Reviewed 
GenomicsInvasive Pulmonary Aspergillosis Diagnosis via Peripheral Blood Metagenomic Next Generation Sequencing
Invasive Pulmonary Aspergillosis Diagnosis via Peripheral Blood Metagenomic Next Generation Sequencing
PRJEB43573 | ENA
GenomicsTranscriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis
Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis
PRJNA412263 | ENA
GenomicsSpatial transcriptomics of in vivo invasive trancheobronchitis biopsies obtained from patients with influenza-associated pulmonary aspergillosis or COVID-19-associated pulmonary aspergillosis
Spatial transcriptomics of in vivo invasive trancheobronchitis biopsies obtained from patients with influenza-associated pulmonary aspergillosis or COVID-19-associated pulmonary aspergillosis
PRJNA813601 | ENA
TranscriptomicsGenome-Wide Expression Profiling Reveals S100B as Biomarker for Invasive Aspergillosis
Invasive aspergillosis (IA) is a devastating opportunistic infection and its treatment constitutes a considerable burden for the health care system. Immunocompromised patients are at an increased risk for IA, which is mainly caused by the species Aspergillus fumigatus. An early and reliable diagnosi...
ORGANISM(S): Homo sapiens 
2016-03-31 | E-GEOD-78000 | biostudies-arrayexpress
GenomicsRapidly and Reconditely Progressing Small Cell Lung Cancer with Invasive Pulmonary Aspergillosis: A Case Report and Literature Review
Rapidly and Reconditely Progressing Small Cell Lung Cancer with Invasive Pulmonary Aspergillosis: A Case Report and Literature Review
PRJEB44259 | ENA
TranscriptomicsTranscriptional profiling of ATCC46645 strain and isogenic M-NM-^TpacC Aspergillus fumigatus mutant during murine infection
In lung diseases caused by the major mould pathogen Aspergillus fumigatus the pulmonary epithelium is destroyed by invasive growth of fungal hyphae, a process thought to require fungal proteases. Here we show that the A. fumigatus pH-responsive transcription factor PacC governs expression of secrete...
ORGANISM(S): Aspergillus fumigatus 
2014-10-20 | E-GEOD-54810 | biostudies-arrayexpress
TranscriptomicsEffect of amphotericin B on Aspergillus fumigatus
Amphotericin B (AMB) is the most widely used polyene antifungal drug for the treatment of systemic fungal infections including invasive aspergillosis. We aimed to understand molecular targets of AMB in Aspergillus fumigatus (Afu) by genomic approaches. Amphotericin B (AMB) is the most widely used p...
ORGANISM(S): Aspergillus fumigatus 
2010-05-26 | E-GEOD-10505 | biostudies-arrayexpress
OtherSpatial transcriptomics of in vivo invasive trancheobronchitis biopsies obtained from patients with influenza-associated pulmonary aspergillosis or COVID-19-associated pulmonary aspergillosis
To assess whether transcriptional differences exist in the epithelial tissue and the inflammatory infiltrate of invasive Aspergillus tracheobronchitis in patients with severe influenza or severe COVID-19, we performed GeoMx spatial transcriptomics on four biopsy samples in total: two of patients wit...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens 
2022-08-24 | GSE198096 | GEO
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