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Proteomics workflows have traditionally been divided into discovery-based and targeted approaches, with instrumentation optimized for each. Discovery experiments typically utilize high-resolution analyzers such as the Orbitrap™, while targeted workflows rely on the sensitivity and specificity of tri...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) Xenopus laevis (African clawed frog) 
2025-09-08 | PXD062540 | Pride
The project aims to evaluate the use of a linear ion trap to increase the sensitivity of multiplexed single-cell proteomics. Using diluted mouse peptide samples from C10 and Raw, we compared the proteome coverages, data missingness, and quantification performance between linear ion trap and Orbitrap...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-08-22 | MSV000090178 | MassIVE
Identification of human plasma by LC-MSMS with orbital ion trap after collection over quaternary amine resin and digestion with trypsin.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055594 | Pride
Identification of proteins from normal human plasma by LC-MSMS with linear ion trap after collection over quaternary amine resin and digestion with trypsin.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055704 | Pride
The development of targeted assays that monitor biomedically relevant proteins is an important step in bridging discovery experiments to large scale clinical studies. Targeted assays are currently unable to scale to hundreds or thousands of targets. We demonstrate the generation of large-scale assay...
ORGANISM(S): Homo Sapiens Gallus Gallus 
2026-01-12 | PXD065471 | panorama
Although only a few years old, the combination of a linear ion trap with an Orbitrap analyzer has become one of the standard mass spectrometers to characterize proteins and proteomes. Here we describe a novel version of this instrument family, the Orbitrap Elite, which is improved in three main area...
ORGANISM(S): Homo sapiens (Human) 
2013-10-10 | PXD000508 | Pride
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