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We have demonstrated that water-soluble zinc ionophores can be administered to mice at relatively high doses and inhibit the growth of A549 lung cancer cells grown in xenograft models. Gene expression profiles of tumor specimens harvested from mice four hours after treatment confirmed that the activ...
ORGANISM(S): Homo sapiens 
2007-02-07 | GSE6962 | GEO
Metagenomics support probiotics as key alternatives to ionophores in broiler production
We have shown that water solubilized versions of a zinc ionophore increase intracellular concentrations of free zinc and have antiproliferative activity in exponential phase A549 lung cancer cultures. The gene expression profiles of A549 lung cancer cultures treated with the lead compound PCI-5002 r...
ORGANISM(S): Homo sapiens 
2007-02-07 | GSE6960 | GEO
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