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The pentameric glycine receptor (GlyR), comprising the α1 and β subunits, is a major inhibitory ionotropic receptor in brainstem and spinal cord. GlyRs interact with gephyrin (GPHN), a scaffold protein that anchors the GlyR in the plasma membrane and enables it to form clusters in glycinergic postsy...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-12 | PXD017151 | Pride
Background. Circular RNAs (circRNAs) play an important role in the occurrence and development of diseases. However, the role of circRNAs in male smokers with chronic obstructive pulmonary disease (COPD) remains unclear. Methods. Stable COPD patients and healthy controls were recruited. Peripheral bl...
ORGANISM(S): Homo sapiens 
2024-06-09 | GSE268499 | GEO
Cadmium (Cd2+) is a persistent neurotoxic trace metal, yet the native protein targets and protein assemblies associated with cadmium exposure in brain tissue remain incompletely defined. Here, we developed Cd-IMAC-MS, a non-denaturing workflow that couples Cd2+-charged nitrilotriacetic acid (NTA) af...
ORGANISM(S): Rattus Norvegicus 
Construction of a ceRNA network and screening of potential biomarkers and molecular targets in male smokers with chronic obstructive pulmonary disease
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