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Reactive oxygen species have been established to play a critical role in pancreatic carcinogenesis. One of the main antioxidant enzymes is mitochondrial superoxide dismutase (Sod2). Sod2 has been shown to affect tumor initiation and metastatic progression in various cancer types. The impact of Sod2 ...
ORGANISM(S): Mus musculus 
CuZn-superoxide dismutase (CuZn-SOD) and ascorbate peroxidase (APX) constitute first line of defence against oxidative stress. In the present study, PaSOD and RaAPX genes from Potentilla atrosanguinea and Rheum australe, respectively were overexpressed individually as well as in combination in Arabi...
ORGANISM(S): Arabidopsis thaliana 
This transcription profiling time course experiment was conducted in order to analyze the cellular response of the plasmid-free expression system E.coli BL21(DE3)::TN7 to high level expression of recombinant human super-oxide-dismutase (SOD).Three biological replicates were generated by usi...
ORGANISM(S): Escherichia coli 
IMS-MS data for Cu/Zn-Superoxide Dismutase (from bovine erythrocytes). Experiments were conducted on two different IMS platforms (DTIMS and TIMS) to compare the CCS values obtained under different types of IMS. Three separate solution conditions were used for the DTIMS data in order to obtain CCS va...
ORGANISM(S): Bovine (from Erythrocytes) 
Within this project, two Arabidopsis tDNA mutants deficient in iron superoxide dismutase FSD1 were exposed to 8h long treatment with methyl viologen. Differential, LC MSMS base proteomics was performed in order to elucidate the mechanisms of the role of FSD1 in oxidative stress tolerance
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-03-18 | PXD028328 | Pride
During its life cycle Leishmania undergoes extreme environmental changes, alternating between insect vectors and vertebrate hosts. In mammals the parasites replicate within parasitophorous vacuoles of macrophages, compartments that contain low concentrations of iron. Here we show that stimulation of...
ORGANISM(S): Leishmania amazonensis 
Elemental stoichiometry of biomass is a focal point that connects different biogeochemical cycles. Yet, the mechanistic underpinnings of elemental stoichiometry are poorly quantified in many cases. We combined targeted and untargeted metaproteomics, Bayesian statistical modelling, and geochemical me...
ORGANISM(S): environmental samples <diatoms environmental samples <haptophytes 
2026-08-13 | PXD076644 | Pride
Efficient and economical iron metabolism of Aspergillus fumigatus protects its mitochondria in the absence of Mn-superoxide dismutase
Switch of mitochondrial superoxide dismutase into a prooxidant peroxidase in manganese-deficient cells
Saccharomyces cerevisiae is exposed to freeze-thaw stress in commercial processes including frozen dough baking. The cell viability and fermentation activity after freeze-thaw were dramatically decreased due to freeze-thaw injury. Because freeze-thaw injury involves complex phenomena, the mechanis...
ORGANISM(S): Saccharomyces cerevisiae 
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