Sort   by:  
 Page size 
ProteomicsProteomic Analysis on the Mechanism of Iron-Compensation Substitute for Manganese Deficiency of Streptococcus pneumoniae
Iron (Fe) and Manganese (Mn) are essential for bacterial survival and virulence as they are involved in catalysis, infection and biofilm formation. The basal metabolism of pathogenic bacteria would be disturbed by the deficiency of metal ions in the host environment. In this study, we found that Str...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2023-09-30 | PXD008652 | Pride
Manganese deficiency Iron-compensation Proteomic Streptococcus pneumoniae 
UnknownCompensation-Like Temperature and Spin-Flip Switch in Strained Thulium Iron Garnet Thin Films: Tuning Sublattice Interactions for Ferrimagnetic Spintronics<sup>†</sup>.
Not available
S-EPMC12305490 | biostudies-literature
TranscriptomicsA Switch in Iron Transport Mechanisms Defines Novel Forms of Congenital Chronic Kidney Disease [P60 Tfr1KO;KspCre]
Periconceptual maternal iron deficiency (FeD) is a worldwide problem resulting in prematurity and low birth weights. Yet, it is not known whether FeD affects all developing tissues, or rather targets specific lineages. To address these questions, we investigated the targeting of the kidney by FeD. W...
ORGANISM(S): Mus musculus 
2025-09-08 | GSE100253 | GEO
TranscriptomicsA Switch in Iron Transport Mechanisms Defines Novel Forms of Congenital Chronic Kidney Disease [P15 FeD]
Periconceptual maternal iron deficiency (FeD) is a worldwide problem resulting in prematurity and low birth weights. Yet, it is not known whether FeD affects all developing tissues, or rather targets specific lineages. To address these questions, we investigated the targeting of the kidney by FeD. W...
ORGANISM(S): Mus musculus 
2025-09-08 | GSE100252 | GEO
TranscriptomicsA Switch in Iron Transport Mechanisms Defines Novel Forms of Congenital Chronic Kidney Disease [P13 Tfr1KO;Six2Cre]
Periconceptual maternal iron deficiency (FeD) is a worldwide problem resulting in prematurity and low birth weights. Yet, it is not known whether FeD affects all developing tissues, or rather targets specific lineages. To address these questions, we investigated the targeting of the kidney by FeD. W...
ORGANISM(S): Mus musculus 
2025-09-08 | GSE100251 | GEO
UnknownAuto-oscillations and directional magnon emission induced by spin current injection into large magnetic volumes.
Not available
S-EPMC12474986 | biostudies-literature
ProteomicsPerinatal iron restriction is associated with changes in neonatal cardiac function and structure in a sex-dependent manner
Iron deficiency (ID) is common during gestation and in early infancy and can alter developmental trajectories with lasting consequences on cardiovascular health. While the effects of ID and anemia on the mature heart are well documented, comparatively little is known about their effects and mechanis...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-10-03 | PXD043588 | Pride
Nutrition Anemia Hypoxia 
OtherGenome-wide synthetic lethal screen unveils novel CAIX – NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors.
Hypoxia is an important clinicopathological feature of solid tumours that limits response to therapy. Carbonic Anhydrase IX (CAIX) is a hypoxia-induced, pH regulator that has emerged as a viable therapeutic target. Targeting CAIX has demonstrated promise in difficult to treat preclinical models of b...
ORGANISM(S): Homo sapiens 
2021-08-28 | GSE167481 | GEO
UnknownA humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the blood-brain barrier.
Not available
S-EPMC12799929 | biostudies-literature
UnknownIron allocation to chloroplast proteins depends on the DNA-binding protein WHIRLY1.
Not available
S-EPMC12174181 | biostudies-literature
Sort   by:  
 Page size