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ProteomicsAging-triggered iron-rich insoluble protein aggregates in the spleen originate chiefly from red pulp macrophages.
Both iron homeostasis and erythropoiesis are known to be affected by aging. Iron needs in mammals are met primarily by iron recycling from senescent red blood cells (RBCs), a task chiefly accomplished by red pulp macrophages (RPMs) in the spleen. Given that RPMs continuously process iron, their cell...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-02 | PXD038660 | Pride
Iron-rich protein aggregates Iron-dextran injection Mouse Red pulp macrophages Spleen 
TranscriptomicsThe effect of iron dextran on the transcriptome of hippocampus in Rongchang piglet
The chain of events leading from oxidation stress is still barely understood. With the emergence of high-throughput sequencing, it is now possible to discover many different biological components simultaneously. Using RNA-seq technology, we sequenced the complete transcriptome of hippocampus of Rong...
ORGANISM(S): Sus scrofa 
2018-12-15 | GSE76007 | GEO
UnknownFerritin But Not Iron Increases in Retina Upon Systemic Iron Overload in Diabetic and Iron-Dextran Injected Mice.
Not available
S-EPMC10019492 | biostudies-literature
UnknownDextran coated bismuth-iron oxide nanohybrid contrast agents for computed tomography and magnetic resonance imaging.
Not available
S-EPMC4251562 | biostudies-literature
UnknownPEG/Dextran Double Layer Influences Fe Ion Release and Colloidal Stability of Iron Oxide Nanoparticles.
Not available
S-EPMC5844897 | biostudies-literature
GenomicsSus scrofa
The effect of iron dextran on the transcriptome of hippocampus in Rongchang piglet
PRJNA305992 | ENA
UnknownOne Iron Injection Is Not Enough-Iron Status and Growth of Suckling Piglets on an Organic Farm.
Not available
S-EPMC6770926 | biostudies-literature
TranscriptomicsMyeloid FtH deficiency accelerates kidney disease by inducing Snca and ferroptosis [Fe treatment WT-KO]
Following kidney injury, we observed increased iron depsoition in kidneys of myeloid specific FtH deficient (FtHΔ/Δ) mice when compared to wild-type (FtHfl/fl) kidneys. To explore mechanisms coordinating increased iron accumulation in FtHΔ/Δ kidneys, we employed a parenterally induced iron overload ...
ORGANISM(S): Mus musculus 
2025-03-17 | GSE290560 | GEO
UnknownThe Effects of the Combination of Oral Lactoferrin and Iron Injection on Iron Homestasis, Antioxidative Abilities and Cytokines Activities of Suckling Piglets.
Not available
S-EPMC6680753 | biostudies-literature
UnknownCombined Injection for Control of Iron-Deficiency Anemia and Coccidiosis in Piglets Decreases Stress at Management Time.
Not available
S-EPMC11310942 | biostudies-literature
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