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GenomicsPerturbed adult sperm methylome after in utero undernutrition is associated with transmission of metabolic disease
The pre and postnatal environment can affect both an individual’s risk of adult onset metabolic disease and that of subsequent generations. Although animal models and epidemiological data implicate epigenetic inheritance, little is known of the mechanisms involved. In a robust intergenerational mo...
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-58747 | biostudies-arrayexpress
TranscriptomicsAccelerated Postnatal Growth Increases Lipogenic Gene Expression and Adipocyte Size in Low-Birth Weight Mice
OBJECTIVE: To characterize the hormonal milieu and adipose gene expression in response to catch-up growth (CUG), a growth pattern associated with obesity and diabetes risk, in a mouse model of low birth weight (LBW). RESEARCH DESIGN AND METHODS: ICR mice were food restricted by 50% from gestational ...
ORGANISM(S): Mus musculus 
2010-03-04 | E-GEOD-16083 | biostudies-arrayexpress
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