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TranscriptomicsGene expression Tet-mev-1 mouse fed either normal diet or high fat high sucrose diet compared with wild type mouse
To assess the effect of steatosis and oxidative stress on progression of liver fibrosis, we have employed whole genome microarray expression profiling as a discovery platform to identify genes that are related with oxidative stress- and steatosis-induced hepatic fibrogenesis. When wild type mice wer...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-68632 | biostudies-arrayexpress
ProteomicsFFPE proteomics for hepatocellular carcinoma
Formalin-fixed paraffin-embedded (FFPE) tissues are crucial clinical archives linked with long-term follow-up data, yet the suitability of deep proteomic analysis on samples stored over 30 years remains largely unexplored. This study aimed to verify the feasibility of deep proteomic analysis on extr...
ORGANISM(S): Homo Sapiens (human) 
2026-04-01 | PXD062456 | JPOST Repository
ProteomicsOld FFPE proteomics of hepatocellular carcinoma
Archival formalin-fixed, paraffin-embedded (FFPE) tissues are invaluable resources for translational research, as clinical outcomes and treatment histories are often available. FFPE blocks provide a standardized and cost-effective alternative to frozen specimens, with formalin-induced protein crossl...
ORGANISM(S): Homo Sapiens (human) 
2026-10-06 | PXD070497 | JPOST Repository
ProteomicsMethod optimization for FFPE proteomics of hepatocellular carcinoma
Archival formalin-fixed, paraffin-embedded (FFPE) tissues are invaluable resources for translational research, as clinical outcomes and treatment histories are often available. FFPE blocks provide a standardized and cost-effective alternative to frozen specimens, with formalin-induced protein crossl...
ORGANISM(S): Homo Sapiens (human) 
2026-10-06 | PXD070191 | JPOST Repository
ProteomicsProteomics analysis of proteins co-immunoprecipitated with MIDN-Flag in PC-12 cells
We have previously identified midnolin (MIDN) as a genetic risk factor for Parkinson's disease. However, the molecular entity of MIDN that regulates neuronal phenotypes remains unclear. To investigate the molecular function of MIDN, we examined proteins associated with MIDN in PC-12 cells. We perfor...
ORGANISM(S): Rattus Rattus (black Rat) 
2024-09-13 | PXD053265 | JPOST Repository
ProteomicsProteomic analyses of iron deprived NK92 cells with deferoxamine or PPMX-T003
This work aims to detect the differentially expressed proteins between transferrin receptor 1 inhibition and iron chelation in a natural killer cell lymphoma-derived cell line NK92. Cells were treated with 500 μM deferoxamine or 10 μg/mL PPMX-T003 (an anti-transferrin receptor 1 inhibitory antibody)...
ORGANISM(S): Homo Sapiens (human) 
2025-07-04 | PXD059223 | JPOST Repository
ProteomicsPeptide mapping and intact mass analysis of RBD protein from a SARS-CoV-2 omicron variant (RBDom)
RBD protein from the SARS-CoV-2 omicron variant (RBDom) was produced in Komagataella phaffii. Peptide mapping and intact mass analysis of RBDom were performed by LC/MS. Proteins were identified using BioPharma Finder software.
ORGANISM(S): Komagataella Phaffii 
2024-10-30 | PXD057342 | JPOST Repository
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