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TranscriptomicsLung cancer
Two prognostically significant subtypes of high-grade lung neuroendocrine tumors independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles. BACKGROUND: Classification of high-grade neuroendocrine tumors (HGNT) of the lung currently recognises large-ce...
ORGANISM(S): Homo sapiens 
2004-02-10 | E-GEOD-1037 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in GBS6 cells after EWS-POU5F1 knockdown
Our objective is to clarify the function of EWS-POU5F1 chimera. Specifially, GBS6 cells were established from an undifferentiated bone sarcoma carrying translocation t(6;22)(p21;q12). The translocation resulted in a gene fusion between EWS and POU5F1. Gene expression analysis of t(6;22) undifferenti...
ORGANISM(S): Homo sapiens 
2009-05-31 | E-GEOD-12320 | biostudies-arrayexpress
TranscriptomicsGene repression with H3K27me3 modification in human small cell lung cancer
Small cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis due to early dissemination and rapid growth. We here analyze gene expression profile of 23 clinical SCLC samples. EZH2 was found to be highly expressed in SCLC samples compared to 42 normal tissues including the normal lun...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-43346 | biostudies-arrayexpress
TranscriptomicsIdentification of CpG island methylator phenotype predicts the prognosis of small cell lung cancer
We analyzed 28 fresh frozen samples from pure SCLC patients and 13 noncancerous lung tissues, using the Illumina Infinium 27k Human DNA methylation Beadchip v1.2 Background: Small cell lung cancer (SCLC) accounts for 13-15% of new lung cancer cases in worldwide and has the poor therapeutic outcomes ...
ORGANISM(S): Homo sapiens 
2013-08-29 | E-GEOD-50412 | biostudies-arrayexpress
UnknownQuantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues.
Not available
S-EPMC11406184 | biostudies-literature
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