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MetabolomicsCommunity-integrated multi-omics facilitates screening and isolation of the organohalide dehalogenation microorganism

A variety of anthropogenic organohalide contaminants generated from industry are released into the environment, and thus cause serious pollution that endangers human health. In the present study, we investigated the microbial community composition of industrial saponification wastewater using 16S...

2022-11-21 | MTBLS3916 | MetaboLights
MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation - DIA lipid mediator validation

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1382 | MetaboLights
ProteomicsNo One-Size-Fits-All: Method-Dependent Recovery of Distinct EV Subsets Across 11 Plasma derived EV Isolation Methods
We evaluated eleven EV isolation methods to define their performance charac-teristics and optimal applications. EVs were quantified by NanoFCM, profiled for tetraspanins (CD9, CD63, CD81) via MSD assays, and further characterized by LC-MS/MS proteomics.
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD075093 | Pride
Reproducibility Extracellular vesicles (evs) Isolation methods Standardization Liquid biopsy Proteomics Biomarkers 
GenomicsRNA Isolation Methods - Diverse Biofluids
RNA Isolation Methods - Diverse Biofluids
PRJNA1013972 | ENA
GenomicsColorectal cancer cell supermeres isolation methods
Colorectal cancer cell supermeres isolation methods
PRJNA1136963 | ENA
ProteomicsProteomic Analysis of Wharton’s Jelly Mesenchymal Stem Cells Isolated by Different Methods
Wharton’s Jelly mesenchymal stem cells (WJ-MSC) are stem cells from the umbilical cord, known for their regenerative properties. They offer advantages like unlimited availability, non-invasive and low-cost isolation, and minimal ethical concerns. WJ-MSCs are promising for allogeneic cell therapy, wi...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD063958 | Pride
Wharton’s jelly mesenchymal stem cells Proteomic Isolation methods 
ProteomicsCharacterization of equine bronchoalveolar lavage fluid extracellular vesicle proteomes across four isolation methods
Growing evidence supports the importance of extracellular vesicle (EV) as mediators of communication in pathological processes, including those underlying respiratory disease. However, establishing methods for isolating and characterizing EVs remains challenging, particularly for respiratory samp...
ORGANISM(S): Equus caballus (Horse) 
2025-05-07 | PXD054702 | Pride
Methods optimization Respiratory Bronchoalveolar lavage Extracellular vesicles Equine Proteome Cell surface markers Lc-ms/ms 
GenomicsComparison of EVs isolation methods for miRNAs sequencing
Comparison of EVs isolation methods for miRNAs sequencing
PRJNA928492 | ENA
GenomicsSmall RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation
Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation
PRJNA671225 | ENA
GenomicsSmall RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation
Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation
PRJNA671227 | ENA
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