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MetabolomicsStable Isotope–Assisted Plant Metabolomics: Combination of Global and Tracer-Based Labeling for Enhanced Untargeted Profiling and Compound Annotation
Untargeted approaches and thus biological interpretation of metabolomics results are still hampered by the reliable assignment of the global metabolome as well as classification and (putative) identification of metabolites. In this work we present an liquid chromatography-mass spectrometry (LC-MS)-b...
2020-02-09 | MTBLS1217 | MetaboLights
MetabolomicsTwo-Channel Chemical Isotope Labeling Metabolomics Analysis of Human Fecal Samples

Global metabolomics study of the amine and carboxyl submetabolomes of 16 human fecal samples.

2026-09-23 | MTBLS13531 | MetaboLights
MetabolomicsgeoRge: A Computational Tool To Detect the Presence of Stable Isotope Labeling in LC/MS-Based Untargeted Metabolomics
Studying the flow of chemical moieties through the complex set of metabolic reactions that happen in the cell is essential to understanding the alterations in homeostasis that occur in disease. Recently, LC/MS-based untargeted metabolomics and isotopically labeled metabolites have been used to facil...
2015-09-15 | MTBLS213 | MetaboLights
MetabolomicsSingle-cell thiol profiling enabled by live-cell labeling reveals metabolic heterogeneity in ferroptosis

Raw data of both bulk and single-cell metabolomics. It includes all MS, LC-MS and LC-MS/MS raw data associated with the article 'Single-cell thiol profiling enabled by live-cell labeling reveals metabolic heterogeneity in ferroptosis'.

2026-02-14 | MTBLS13900 | MetaboLights
MetabolomicsPronounced uptake and metabolism of organic substrates by diatoms revealed by pulse-labeling metabolomics
Diatoms contribute as a major group of microalgae to approximately 20% of the global carbon fixation. In the plankton, these algae are exposed to a plethora of metabolites, especially when competing algae are lysed. In line with evidence that these phototrophs can also engage in heterotrophy we aske...
2021-12-09 | MTBLS2333 | MetaboLights
MetabolomicsMass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

Mass spectrometry imaging (MSI) visualises molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labelling provided spatial analyses of phosphatidylcholine (PC) metabolism in mouse lungs. D...

2020-10-30 | MTBLS2075 | MetaboLights
TranscriptomicsPhylogenetic patterns in the microbial response to resource availability: amino acid incorporation in San Francisco Bay
Aquatic microorganisms are typically identified as either oligotrophic or copiotrophic, representing trophic strategies adapted to low or high nutrient concentrations, respectively. Here, we sought to take steps towards identifying these and additional adaptations to nutrient availability with a qua...
ORGANISM(S): marine metagenome 
2014-03-26 | E-GEOD-56119 | biostudies-arrayexpress
ProteomicsHyperSCP: Combining Isotopic and Isobaric Labeling for Higher Throughput Single-Cell Proteomics
Recent developments in mass spectrometry-based single-cell proteomics (SCP) have resulted in dramatically improved sensitivity, yet the relatively low measurement throughput remains a limitation. Isobaric and isotopic labeling methods have been separately applied to SCP to increase throughput throug...
ORGANISM(S): Homo sapiens (Human) 
2023-07-11 | PXD040455 | Pride
Multiplex Single-cell proteomics High-throughput 
Proteomicsone step carboxyl group isotopic labeling for quantitative analysis of N-glycopeptide by Mass Spectrometry
Glycosylation is one of the most common and important post-translational modifications. Quantitative analysis of intact N-glycopeptides is critical to understand the role of protein glycosylation in physiological and pathological processes. In this work, we developed a novel approach called methylam...
ORGANISM(S): Homo Sapiens 
PXD021104 |
ProteomicsInverse Stable Isotopic Labeling of NRPS
Inverse Stable Isotopic labeling of NRPS compound
ORGANISM(S): Methylobacter Tundripaludum (ncbitaxon:173365) 
2024-02-29 | MSV000094208 | MassIVE
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