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GenomicsTET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [DREAM]
We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-44038 | biostudies-arrayexpress
GenomicsTET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [MeDIP-Seq]
We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-44036 | biostudies-arrayexpress
UnknownPrediction of surface roughness based on fused features and ISSA-DBN in milling of die steel P20.
Not available
S-EPMC10518346 | biostudies-literature
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [DREAM-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53025 | biostudies-arrayexpress
UnknownEvaluation of ISSA proactive leading indicators for safety, health and well-being: Application of multi-criteria decision-making methods based on hesitant fuzzy.
Not available
S-EPMC12404562 | biostudies-literature
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [ChIP-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53023 | biostudies-arrayexpress
ProteomicsExamining pathways of iron and sulfur acquisition, trafficking, deployment, and storage in mineral-grown methanogen cells
Methanogens were recently shown to reduce pyrite (FeS2) generating aqueous iron-sulfide (FeS(aq)) clusters that are likely assimilated as a source of Fe and S. Here, we compare the phenotype of Methanococcus voltae when grown with FeS2 or ferrous iron (Fe(II)) and sulfide (HS-). Differential proteom...
ORGANISM(S): Methanococcus voltae A3 
2021-07-07 | PXD024933 | Pride
Iron-sulfur cluster Pyrite Methanogen Fes2 Fes Mackinawite 
UnknownInduction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia.
Not available
S-EPMC2234065 | biostudies-literature
UnknownColorectal cancer screening: An updated review of the available options.
Not available
S-EPMC5537177 | biostudies-literature
TranscriptomicsTET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [RNA-seq]
We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-49833 | biostudies-arrayexpress
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