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TranscriptomicsDownstream genes regulated by TSHZ2 in MCF-7 cells
To clarify downstream genes regulated by TSHZ2, MCF-7 cells were lentivirally transduced by TSHZ2 and its control LacZ and served their RNA samples for gene expression analysis using AGILENT human 8x60K cDNA microarray. Array analysis of MCF-7 cells expressing either TSHZ2 or LacZ. 1 color method wa...
ORGANISM(S): Homo sapiens 
2016-01-11 | E-GEOD-64351 | biostudies-arrayexpress
TranscriptomicsIdentification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation
Chromosomes and genes are non-randomly arranged within the mammalian cell nucleus. Clustering of genes is of great significance in transcriptional regulation. However, the relevance of gene clustering in their expression during differentiation of neural precursor cells (NPCs) into astrocytes remains...
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-66097 | biostudies-arrayexpress
TranscriptomicsGLI1-regulated genes in human mammary epithelial cells and human breast cancer cells
To clarify transcriptional target genes of GLI1 in human mammary epithelial cells and breast cancer cells, primary culture cells of human mammary epithelium HMEC and breast cancer cell line MCF-7 were lentivirally transduced by either GLI1 or its control LacZ. Their RNA samples were served for expre...
ORGANISM(S): Homo sapiens 
2015-04-28 | E-GEOD-64350 | biostudies-arrayexpress
TranscriptomicsStepwise development of hematopoietic stem cells from embryonic stem cells
The cellular ontogeny of hematopoietic stem cells (HSCs) remains poorly understood because their isolation from and their identification in early developing small embryos are difficult. We attempted to dissect early developmental stages of HSCs using an in vitro mouse embryonic stem cell (ESC) diffe...
ORGANISM(S): Mus musculus 
2009-03-18 | E-GEOD-15053 | biostudies-arrayexpress
ProteomicsRat liver treated by PCN
The combination analyses of transcriptomics, proteomics, phosphoproteomics, and metabolomics in rat liver after repeated oral doses of PXR agonist, PCN, for 7 days were conducted to understand the roles for PXR on non-genotoxic signaling and energy homeostasis. mRNA and proteins in homogenate supern...
ORGANISM(S): Rattus Rattus (black Rat) 
2018-01-01 | PXD006305 | JPOST Repository
ProteomicsHuman tissue microsomed by MRM, MRMHR and SWATH
The purpose of the present study was to examine simultaneously the absolute protein amounts of 152 membrane and membrane-associated proteins, including 30 metabolizing enzymes and 107 transporters, in pooled microsomal fractions of human liver, kidney and intestine by means of SWATH-MS with stable i...
ORGANISM(S): Homo Sapiens (human) 
2018-01-01 | PXD008265 | JPOST Repository
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