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MetabolomicsDistribution of RESV and its metabolite peaks in mouse tissues after oral and skin administration
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
2014-12-15 | MTBLS125 | MetaboLights
MetabolomicsResveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
MTBLS127 | MetaboLights
MetabolomicsAbsorption efficiency of RESV through mouse skin using 3 bases in different tissues
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
2014-12-15 | MTBLS126 | MetaboLights
TranscriptomicsGenomic profiling of gastric adenomas by array-based comparative genomic hybridization
In this study, we investigated CNAs of 20 gastric CIS (Vienna category 4.2) and 20 adenomas, including 7 low-grade adenomas (LGA; Vienna category 3) and 13 high-grade adenomas (HGA; Vienna category 4.1), by 244k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 gastric ad...
ORGANISM(S): Homo sapiens 
2010-06-18 | E-GEOD-19574 | biostudies-arrayexpress
TranscriptomicsExpression data from common myeloid progenitor cells (CMP) of C57BL6 mouse
Common myeloid progenitor cells from murine bone marrow were sorted according to ROS content using FACS with H2-DCFDA staining. We compared gene expression profile between CMP with low-ROS levels and those with high-ROS levels. We analysed function of ROS in differentiation step from CMP to MEP.
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-57469 | biostudies-arrayexpress
ProteomicsLFQ of 3-phosphoglyceroyl lysine peptides from WT and DJ-1 KO HeLa cells
WT or DJ-1 KO HeLa cells (n=3) were lysed in 500 μL of 6 M guanidine-HCl, 100 mM HEPES-NaOH, pH 7.5, 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication, followed by centrifugation at 20,000 x g for 15 min at 4 ºC. The supernatants were recovered and proteins (1 mg each) ...
ORGANISM(S): Homo Sapiens (human) 
2025-05-07 | PXD063699 | JPOST Repository
ProteomicsLFQ of carboxymethyl/carboxyethyl lysine peptides from WT and DJ-1 KO HeLa cells
WT or DJ-1 KO HeLa cells (n=3) were lysed in 500 μL of 6 M guanidine-HCl, 100 mM HEPES-NaOH, pH 7.5, 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication, followed by centrifugation at 20,000 x g for 15 min at 4 ºC. The supernatants were recovered and proteins (1 mg each) ...
ORGANISM(S): Homo Sapiens (human) 
2025-05-07 | PXD063705 | JPOST Repository
ProteomicsLFQ of carboxymethyl/carboxyethyl lysine peptides from MGO- or GO-treated HeLa cells
HeLa cells (n=2) were treated with cell culture media containing 2 mM MGO or GO for 2 h and lysed in 6 M guanidine-HCl, 100 mM HEPES-NaOH, pH 7.5, 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication, followed by centrifugation at 20,000 x g for 15 min at 4 ºC. The superna...
ORGANISM(S): Homo Sapiens (human) 
2025-05-07 | PXD063706 | JPOST Repository
TranscriptomicsIdentification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [cell culture]
Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated about how MYC, an archetypical oncogene, is regulated by miRNAs, especially through a mechanism involving the MYC cofactor(s). In this study, we aimed a...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-66758 | biostudies-arrayexpress
TranscriptomicsIdentification of mir-342-3p functionally associated with transcriptional activity of MYC in lung cancer [patients]
Accumulating evidence indicates that altered miRNA expression is crucially involved in lung cancer development, but only little has been elucidated about how MYC, an archetypical oncogene, is regulated by miRNAs, especially through a mechanism involving the MYC cofactor(s). In this study, we aimed a...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-66759 | biostudies-arrayexpress
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