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TranscriptomicsEnoxacin_ColonCancer
We show that the small molecule enoxacin, a fluroquinolone used as an antibacterial compound, enhances the production of miRNAs with tumor suppressor functions by its binding to the microRNA biosynthesis protein TRBP. The use of enoxacin in human cell cultures and xenografted, orthotopic and metasta...
ORGANISM(S): Mus musculus 
2011-09-24 | E-TABM-1077 | biostudies-arrayexpress
Proteomics,MultiomicsProtein phosphorylation evolution across 18 fungal species
Protein phosphorylation evolution across 18 fungal species. For each species whole cell extracts were digested separately with trypsin and LysC. Each digest was IMAC enriched and analyzed by LC-MS/MS in technical triplicate on an LTQ Orbitrap Velos using a 120min method. Data was searched against th...
ORGANISM(S): S. Cerevisiae, S. Paradoxus, S. Mikatae, S. Kudriavzevii, S. Bayanus, N. Castellii, C. Glabrata, V. Polyspora, Z. Rouxii, K. Lactis, L. Kluyveri, L. Thermotolerans, L. Waltii, K. Pastoris, M. Guilliermondii, C. Albicans, S. Stipitis, S. Pombe 
2015-12-18 | MSV000079428 | MassIVE
TranscriptomicsExosomes miRNA array submission
MicroRNA microarray profilling analysis was performed on exosomes derived from 4T1 mammary epithelial cancer cells in two culture conditions, hypoxia and normoxia.
ORGANISM(S): Mus musculus 
2014-06-01 | E-MTAB-2361 | biostudies-arrayexpress
UnknownTRP14 is the rate-limiting enzyme for intracellular cystine reduction and regulates proteome cysteinylation
Not available
S-SCDT-10_1038-S44318-024-00117-1 | biostudies-other
TranscriptomicsProfiling data on the developing olfactory/GnRH system reveal cellular and molecular pathways potentially relevant for the Kallmann syndrome.
The olfactory sensory system is formed by the coordinated morphogenesis and differentiation of the peripheral olfactory epithelium (OE) and the anterior forebrain. At early stages, immature olfactory receptor neurons (ORN) elongate their axons to penetrate the brain basement membrane, contact and fo...
ORGANISM(S): Mus musculus 
2014-01-31 | E-GEOD-52800 | biostudies-arrayexpress
TranscriptomicsTranscribed ultraconserved region 339 promotes carcinogenesis by sequestering tumor suppressor microRNAs
The transcribed ultraconserved regions (T-UCRs) are a family of long non-coding RNAs implicated in human carcinogenesis. The mechanism of action of T-UCRs and the factors regulating their expression in human cancers are poorly understood. In this study we show that high expression of uc.339 correlat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-70540 | biostudies-arrayexpress
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