Sort   by:  
 Page size 
TranscriptomicsCell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/abdB-like HOX protein complex
The molecular mechanism defining susceptibility of normal cells to oncogenic transformation may be a valuable therapeutic target. We characterized the cell of origin and its critical pathways in MN1 leukemias. Common myeloid (CMP), but not granulocyte-macrophage progenitors (CMP) could be transforme...
ORGANISM(S): Mus musculus 
2011-05-19 | E-GEOD-22923 | biostudies-arrayexpress
ProteomicsNRDC-IP
IP-MS analysis against endogenous NRDC using megakaryocyte cell lysates.
ORGANISM(S): Homo Sapiens (human) 
PXD009739 | JPOST Repository
TranscriptomicsMicroarray data of mouse MLL-AF10 leukemia cells with or without IKK inhibitor treatment
MLL fusion proteins in leukemia induce aberrant transcriptional elongation and associated chromatin perturbations, however the upstream signaling pathways and activators that recruit or retain MLL oncoproteins at initiated promoters are unknown. Through functional and comparative genomic studies, we...
ORGANISM(S): Mus musculus 
2013-09-19 | E-GEOD-46250 | biostudies-arrayexpress
TranscriptomicsMicroarray data of human leukemia cells MV4;11 with or without IKK inhibitor treatment.
MLL fusion proteins in leukemia induce aberrant transcriptional elongation and associated chromatin perturbations, however the upstream signaling pathways and activators that recruit or retain MLL oncoproteins at initiated promoters are unknown. Through functional and comparative genomic studies, we...
ORGANISM(S): Homo sapiens 
2013-09-19 | E-GEOD-46251 | biostudies-arrayexpress
TranscriptomicsMicroarray data of leukemia cells with or without IKK inhibitor treatment
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-09-19 | E-GEOD-46252 | biostudies-arrayexpress
Sort   by:  
 Page size