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TranscriptomicsExpression data in splenic DC subsets in wild type and Xbp1 deficient mice
Xbp1 is a major transcription factor in the unfolded protein response. To uncover its function in DCs we generated a conditional KO for Xbp1 in dendritic cells. We here compare the expression of mRNAs in two different splenic DC subpopulations, CD8a and CD11b DCs in both WT and KO mice. Reference: I...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-52857 | biostudies-arrayexpress
ProteomicsIRE1alpha promotes reticulophagy in podocytes
Protomics data for "IRE1alpha promotes reticulophagy in podocytes"
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-03-10 | MSV000089032 | MassIVE
TranscriptomicsIRE1alpha is an endogenous substrate of endoplasmic reticulum-associated degradation
Endoplasmic reticulum-associated degradation (ERAD) represents a principle quality control (QC) mechanism to clear misfolded proteins in the ER; however, its physiological significance and the nature of endogenous ERAD substrates remain largely unknown. Here we discover that IRE1alpha, the sensor of...
ORGANISM(S): Mus musculus 
2015-11-04 | E-GEOD-70563 | biostudies-arrayexpress
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