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GenomicsNational Eye Institute Glaucoma Human Genetics Collaboration (NEIGHBOR) Consortium Glaucoma Genome-Wide Association Study

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238.v1.p1 | EGA
UnknownPromoting Healthy Aging During COVID-19.
Not available
S-EPMC8013507 | biostudies-literature
ProteomicsPlasma proteomic signature of major depressive episode in the elderly
Depression is a complex and multifactorial disease, affecting about 6.5% of the elderly population in what is referred to as late-life depression (LLD). Despite its public health relevance, there is still limited information about the molecular mechanisms of LLD. We analyzed the blood plasma of 50 o...
ORGANISM(S): Homo sapiens (Human) 
2023-03-07 | PXD034030 | Pride
Late-life depression  proteomics  aging  senescence 
UnknownDysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells.
Not available
S-EPMC8728893 | biostudies-literature
TranscriptomicsSMAD3 targets in A549 lung epithelial cells
TGF? activates a signal transduction cascade that results in the transcription of genes, primarily through the DNA-binding transcription factor SMAD3. The objective of this study is to identify SMAD3 binding targets and the molecular pathways affected by the TGF?1/SMAD3 signal transduction on a geno...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-26858 | biostudies-arrayexpress
UnknownDivergent Levels of Marker Chromosomes in an hiPSC-Based Model of Psychosis.
Not available
S-EPMC5355568 | biostudies-literature
no omics definedGenotyping of twenty Pseudomonas aeruginosa strains
20 P. aeruginosa strains were genotyped using a custom spotted oligo array (Ausubel P. aruginosa genotyping 4.8K v1), which included primarily oligos for genes present in strain PA14 but absent in PAO1, and oligos for genes present in PAO1 but absent in PA14 (as well as controls).
ORGANISM(S): Pseudomonas aeruginosa 
2006-10-06 | E-MEXP-824 | biostudies-arrayexpress
TranscriptomicsDifferential expression of mouse Grem1+ Vs. Grem1- bone-marrow cells
The gene expression of bone marrow cells of mice enriched for Gremlin1 vs control was measured (n=3). It is not known if endogenous adult mesenchymal stem cells (MSCs) exist.Following culture,perisinusoidal mesenchymal cells can clonally recapitulate the skeletal microenvironment, but this fails to ...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-57729 | biostudies-arrayexpress
UnknownMarker chromosome genomic structure and temporal origin implicate a chromoanasynthesis event in a family with pleiotropic psychiatric phenotypes.
Not available
S-EPMC5995661 | biostudies-literature
UnknownMosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder.
Not available
S-EPMC4038484 | biostudies-literature
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