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MetabolomicsLarge-scale non-targeted plasma metabolomics in the Uppsala Longitudinal Study of Adult Men
The Uppsala Longitudinal Study of Adult Men (ULSAM) study is an ongoing, longitudinal, epidemiologic study started in 1970 and based on men born between 1920 and 1924 in Uppsala, Sweden which were invited to participate at age 50 (N=2,841) [PMID: 9484991]; 81.7% (N=2,322) participated. Individuals w...
2015-03-23 | MTBLS124 | MetaboLights
TranscriptomicsFASCIATED EAR4 encodes a bZIP transcription factor that controls shoot meristem size in maize
fasciated ear4 (fea4) is a semi-dwarfed mutant with fasciated ears and tassels, and greatly enlarged vegetative and inflorescence meristems. Chromatin Immunoprecipitation-sequencing (ChIP-seq) and expression profiling by RNA-seq suggest that fea4 is required to regulate the auxin response and leaf ...
ORGANISM(S): Zea mays 
2015-01-21 | E-GEOD-61954 | biostudies-arrayexpress
UnknownWhole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans.
Not available
S-EPMC6337694 | biostudies-literature
GenomicsMRC HGU IGMM Edinburgh DAC
Data Access Committee EGAC00001000393
EGAC00001000393 | EGA
TranscriptomicsRegulatory Modules Controlling Maize Inflorescence Architecture: mRNA-seq data
In this study we used the maize (Zea mays) inflorescence to investigate gene networks that modulate determinacy, specifically the decision to allow branch growth. We characterized developmental transitions by associating spatiotemporal expression profiles with morphological changes resulting from g...
ORGANISM(S): Zea mays 
2013-11-27 | E-GEOD-51047 | biostudies-arrayexpress
GenomicsTRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
DNA lesions encountered by replicative polymerases threaten genome stability and cell cycle progression. Here we report the identification of mutations in TRAIP, encoding an E3 RING ubiquitin ligase, in patients with microcephalic primordial dwarfism/Seckel syndrome. We establish that TRAIP relocali...
EGAS00001001501 | EGA
TranscriptomicsEvidence of Dynamically Dysregulated Gene Expression Pathways in Hyper-responsive B Cells from African American Lupus Patients
In this report we applied standard and original methods of analysis of gene expression microarray data to delineate differences in the molecular pathways impacted by stimulation of Epstein-Barr virus (EBV) transformed B cells derived from patients with systemic lupus erythematosus (SLE) and normal u...
ORGANISM(S): Homo sapiens 
2012-04-25 | E-GEOD-37573 | biostudies-arrayexpress
TranscriptomicsGene Expression in Myotonic Dystrophy
In order to examine the changes in gene expression between normal and myotonic dystrophic animals, gene expression array studies were done with extensor digitorum longus (EDL) of transgenic HSALR line 20b mice using Affymetrix MOE430 2.0 microarrays. We used EDL muscle from transgenic HSALR line 20b...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-24920 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis in Dicer knock-out mice
The precise mechanisms by which microRNAs (miRNAs) contribute to the dynamic regulation of gene expression during forebrain development are still partly elusive. Here we show that depletion of miRNAs via genetic inactivation of Dicer after the onset of forebrain neurogenesis profoundly impairs the m...
ORGANISM(S): Mus musculus 
2012-11-14 | E-MTAB-1062 | biostudies-arrayexpress
Genomicsena-DATASET-MRCHGUIGMM-07-10-2015-09:16:27:050-356 - samples
BAM files for two WES TRAIP patients
EGAD00001001633 | EGA
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