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TranscriptomicsV(D)J TCR single cell sequencing of mucosal pinch biopsies from patients with ulcerative colitis and primary sclerosing cholangitis concomitant with colitis
Mucosal pinch biopsies from ascending, transverse, descending colon and rectum were obtained from ulcerative colitis (UC) and primary sclerosing cholangitis concomitant with colitis (PSC-UC) patients during routine endoscopies and subjected to 5' single-cell RNA sequencing with V(D)J TCR analysis
ORGANISM(S): Homo sapiens 
2026-06-17 | E-MTAB-14899 | biostudies-arrayexpress
TranscriptomicsV(D)J BCR single cell sequencing of mucosal pinch biopsies from patients with ulcerative colitis and primary sclerosing cholangitis concomitant with colitis
Mucosal pinch biopsies from ascending, transverse, descending colon and rectum were obtained from ulcerative colitis (UC) and primary sclerosing cholangitis concomitant with colitis (PSC-UC) patients during routine endoscopies and subjected to 5' single-cell RNA sequencing with V(D)J BCR analysis
ORGANISM(S): Homo sapiens 
2026-06-17 | E-MTAB-14901 | biostudies-arrayexpress
TranscriptomicsCerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum.
The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical for effective clinical management and prevention of...
ORGANISM(S): Mus musculus 
2014-10-23 | E-GEOD-62594 | biostudies-arrayexpress
TranscriptomicsEvidence of Dynamically Dysregulated Gene Expression Pathways in Hyper-responsive B Cells from African American Lupus Patients
In this report we applied standard and original methods of analysis of gene expression microarray data to delineate differences in the molecular pathways impacted by stimulation of Epstein-Barr virus (EBV) transformed B cells derived from patients with systemic lupus erythematosus (SLE) and normal u...
ORGANISM(S): Homo sapiens 
2012-04-25 | E-GEOD-37573 | biostudies-arrayexpress
Transcriptomics[E-MTAB-599] Mouse Transcriptome
Sequencing the transcriptome of DBAxC57BL/6J mice. To study the regulation of transcription, splicing and RNA turnover we have sequenced the transcriptomes of tissues collected DBAxC57BL/6J mice. We strongly encourage researchers to contact us if there is any queries about referencing or publishing ...
ORGANISM(S): Mus musculus 
2011-07-14 | GSE30617 | GEO
UnknownA trio of simple optimized axisymmetric kinematic dynamos in a sphere.
Not available
S-EPMC6784403 | biostudies-literature
TranscriptomicsTranscription profiling of eyes from wild type and Bma knock-out mice after different lengths of time in a 12:12-hr LD cycle or in constant darkness to identify daily rhythms in ocular gene expression
To explore daily rhythms of ocular gene expression in adult mice we performed the following experiments: i) Mice were entrained to a 12:12-hr light-dark (LD) cycle for 3 weeks. Then mice were transferred to constant darkness (DD) or remained in LD and eyes were collected at four-hour intervals over ...
ORGANISM(S): Mus musculus 
2007-08-24 | E-TABM-285 | biostudies-arrayexpress
MetabolomicsMetabolomic and Metataxonomic Fingerprinting of Human Milk Suggests Compositional Stability over a Natural Term of Breastfeeding to 24 Months
Sparse data exist regarding the normal range of composition of maternal milk beyond the first postnatal weeks. This single timepoint, observational study in collaboration with the 'Parenting Science Gang' citizen science group evaluated the metabolite and bacterial composition of human milk from 62 ...
2022-02-11 | MTBLS1370 | MetaboLights
TranscriptomicsBase-resolution analyses of parent-of-origin and sequence dependent allele specific DNA methylation in the mouse genome (RNA-seq)
Allele specific DNA methylation (ASM) is crucial for genomic imprinting and mammalian development. Here we present a base-resolution, genome-wide allelic DNA methylation map for both CG and non-CG sites in the mouse brain. We found parent-of-origin dependent (imprinted) ASM at 1,952 CGs which form 5...
ORGANISM(S): Mus musculus 
2012-02-15 | E-GEOD-33468 | biostudies-arrayexpress
ModelsSivakumar2011_NeuralStemCellDifferentiation_Crosstalk
Sivakumar2011_NeuralStemCellDifferentiation_Crosstalk This model is generated by integrating BIOMD0000000394 (EGFR), BIOMD0000000395 (Hedgehog), BIOMD0000000396 (Notch) and BIOMD0000000397 (Wnt), to investigate the signalling crosstalk between the four pathways. This model is described in th...
2024-09-02 | BIOMD0000000398 | BioModels
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