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MetabolomicsHERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION
Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...
2025-04-03 | MTBLS5163 | MetaboLights
ProteomicsComparative exo-proteomic analysis of Trichoderma antagonists induced by oomycete mycelium highlights diverse antagonism strategies
Plant-beneficial fungi from the genus Trichoderma (Hypocreales, Ascomycota) can control oomyceteous plant-pathogenic Pythium myriotylum (Peronosporales, Oomycota) and thus serve as bioeffectors for the eco-friendly products of crop protection. However, the underlying mechanisms of microbe-microbe in...
ORGANISM(S): Trichoderma asperellum CBS 433.97 Trichoderma virens Gv29-8 Hypocrea jecorina (strain QM6a) (Trichoderma reesei) Trichoderma atroviride IMI 206040 Trichoderma parepimyces Trichoderma guizhouense 
2024-07-19 | PXD051895 | Pride
Trichoderma Exo-proteins Hydrolyase Antagonism 
TranscriptomicsExpression analysis time-course of Arabidopsis roots to sulfur deficiency
We preformed at time-course of the expression of whole Arabidopsis roots for 3H, 12H, 24H, 48H and 72H after transfer to media lacking sulfur. We combined these data with 13 other datasests and performed a meta-analysis to ask whether a universal stress response exists in Arabidopsis roots. Stress r...
ORGANISM(S): Arabidopsis thaliana 
2011-11-23 | E-GEOD-30098 | biostudies-arrayexpress
TranscriptomicsExpression analysis of developmental stages of Arabidopsis roots exposed to sulfur deficient media
To understand the effect of sulfur deficiency on developmental stages in the root, we dissected the root into four developmental zones after exposure to sulfur deficiency and expression profiled each zone. Stress responses in plants are tightly coordinated with developmental processes, but the inter...
ORGANISM(S): Arabidopsis thaliana 
2011-11-23 | E-GEOD-30100 | biostudies-arrayexpress
GenomicsGenome-wide binding profiles of Sp5 in differentiation mouse embryonic stem cells
We have determined the genome-wide binding profile of the transcription factor Sp5. Flag-tagged Sp5 was targeted to the HPRT locus in A2Lox.cre ES cells to allow for Doxycycline inducible expression. ES cells were cultured as embryoid bodies for 2 days to prime them for germ layer differentiation. C...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-72989 | biostudies-arrayexpress
UnknownAssociation Between Urinary Sodium and Potassium Excretion and Blood Pressure Among Adults in the United States: National Health and Nutrition Examination Survey, 2014.
Not available
S-EPMC5771856 | biostudies-literature
UnknownThe combined effect of encapsulating curcumin and C6 ceramide in liposomal nanoparticles against osteosarcoma.
Not available
S-EPMC4445741 | biostudies-literature
TranscriptomicsDetermination of the Sp5 regulated transcriptome in differentiating ES cells
Sp5 is a target and critical transducer of the Wnt/beta-catenin signaling pathway and is essential for mesoderm differentiation in vertebrate embryos. We established a doxycycline inducible ES cell line to over-express Flag epitope-tagged Sp5 protein in differentiating ES cells which have the capaci...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-73082 | biostudies-arrayexpress
TranscriptomicsDetermination of the Lef1 regulated tanscriptome in differentiating ES cells
Lef1 is a critical transducer of the Wnt/beta-catenin signaling pathway that is essential for mesoderm differentiation in vertebrate embryos. We established a doxycycline inducible ES cell line to over-express Flag-tagged Lef1 in differentiating ES cells which have the capacity to form mesoderm cell...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-73083 | biostudies-arrayexpress
UnknownVitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia.
Not available
S-EPMC5770587 | biostudies-literature
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