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UnknownParity and Risk of Dementia in Women: The Atherosclerosis Risk in Communities Study.
Not available
S-EPMC10541925 | biostudies-literature
UnknownDual-histamine receptor blockade with cetirizine - famotidine reduces pulmonary symptoms in COVID-19 patients.
Not available
S-EPMC7455799 | biostudies-literature
TranscriptomicsSingle cell RNA-seq of human CD8+ T cells binding the IAV HLA-A24/PB1 498-505 tetramer
PBMCs from 4 donors were stained with the influenza A virus HLA-A24/PB1 498-505 tetramer. Two donors (non-LIFT8 and non-LIFT12) showed TCR independent KIR binding to tetramers whereas the other two donors (Non-LIFT14 and Non-LIFT10) showed TCR specific binding. Cells were single-cell sorted on a BD ...
ORGANISM(S): Homo sapiens 
2021-04-08 | E-MTAB-10109 | biostudies-arrayexpress
TranscriptomicsMyeloid lineage switch in pro-B cells generates novel macrophage subsets during homeostasis and inflammation
Here we demonstrate for the first time evidence of lineage switch from B-1 B lymphocyte to a macrophage , or so-called transdifferentiation, occurring in mature cells in vivo. Specifically, using transgenic B6.Mb1-iCre/Rosa26-YFP mice, in which YFP expression is restricted exclusively to B cell line...
ORGANISM(S): Mus musculus 
2018-09-01 | E-MTAB-1878 | biostudies-arrayexpress
TranscriptomicsDicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice
MiRNAs have the potential to regulate cellular differentiation programs. However, miRNA-deficiency in primary hematopoietic stem cells (HSCs) results in HSC depletion in mice, leaving the question of whether miRNAs play a role in early-lineage decisions unanswered. To address this issue, we deleted ...
ORGANISM(S): Mus musculus 
2012-06-17 | E-GEOD-35844 | biostudies-arrayexpress
MetabolomicsA Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection
The potential for commensal microorganisms indigenous to a host (the microbiome or microbiota) to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics systems approach, incorporating proteomics, metabolomics, glycomics, and metagenomics, to explore...
2014-06-24 | MTBLS96 | MetaboLights
TranscriptomicsVirus-Induced Airway Disease in Mice (C57BL/6J, d3)
Analysis of gene expression in lungs of C57BL/6J mice that develop chronic airway disease phenotypes after a single Sendai virus infection, compared with mice treated with UV-inactivated virus. Keywords: disease state analysis Whole lung RNA was analyzed from 3 mice per condition per time point 3 da...
ORGANISM(S): Mus musculus 
2015-03-27 | E-GEOD-61437 | biostudies-arrayexpress
TranscriptomicsNeural Stem/Progenitor Cell Properties of Glial Cells in the Adult Auditory Nerve
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-04-30 | E-GEOD-59417 | biostudies-arrayexpress
TranscriptomicsChemokine Transcripts as Targets of the RNA-Binding Protein HuR in Human Airway Epithelium
HuR is a regulator of mRNA turnover or translation of inflammatory genes through binding to adenylate-uridylate-rich elements (ARE) and related motifs present in the 3’untranslated region (UTR) of mRNAs. We aimed to identify HuR targets in the human airway epithelial cell line BEAS-2B challenged wit...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-25264 | biostudies-arrayexpress
TranscriptomicsNeural Stem/Progenitor Cell Properties of Glial Cells in the Adult Auditory Nerve [cultured auditory nerve cells]
Spiral ganglion neurons (SGNs) and the associated components of the auditory nerve are primary carriers of auditory information from hair cells to the brain. Loss of SGNs occurs with many pathological conditions, resulting in permanent sensorineural hearing loss. Neural stem/progenitors (NSPs) hav...
ORGANISM(S): Mus musculus 
2015-04-29 | E-GEOD-65249 | biostudies-arrayexpress
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