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ProteomicsMouse sciatic nerve LC-MSMS - Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration
The peripheral nervous system (PNS) regenerates after injury. However regeneration is often compromised in case of large lesions, the speed of axon reconnection to their target being critical for successful functional recovery. After injury, mature Schwann cells (SCs) convert into repair cells that ...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-17 | PXD005383 | Pride
Mouse sciatic nerve lc-msms 
TranscriptomicsFunctions of HDAC1 and HDAC2 in Schwann cells during postnatal
The aim of our study is to determine the functions of histone deacetylases (HDACs) 1 and 2 in Schwann cells during postnatal development of the peripheral nervous system (PNS). Schwann cells are the myelinating glial cells of the PNS. At birth, mouse sciatic nerves mature in 2 subsequent phases: 1/ ...
ORGANISM(S): Mus musculus 
2011-02-25 | E-GEOD-27451 | biostudies-arrayexpress
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
UnknownHydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features.
Not available
S-EPMC6269131 | biostudies-literature
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
UnknownUsing multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study.
Not available
S-EPMC11848217 | biostudies-literature
GenomicsA Genomic History of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterised. We generated high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25...
EGAS00001001766 | EGA
TranscriptomicsMutation Order Affects Tumor Evolution and Clinical Course of Disease
Background: Cancers result from accumulation of somatic mutations and their properties are thought to reflect the sum of these mutations. However, little is known about the consequences of altering the order of mutation acquisition. Methods: Mutation order was determined in myeloproliferative neopl...
ORGANISM(S): Homo sapiens 
2014-11-17 | E-MTAB-3086 | biostudies-arrayexpress
UnknownDisease modification and symptom relief in osteoarthritis using a mutated GCP-2/CXCL6 chemokine
Not available
S-SCDT-10_15252-EMMM_202216218 | biostudies-other
Genomicsena-DATASET-UNIBE-07-04-2016-07:41:15:505-596 - samples
Mapped data (bam files) for high-throughput whole genome sequence data for 83 modern Aboriginal Australians
EGAD00001002001 | EGA
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