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TranscriptomicsscRNA-seq of embryonic skin development (developmental time series in full-thickness dorsal skin of mouse embryos)
In this study, we analysed early embryonic skin development (mus musculus; C57BL/6J) at the transcriptional level. Major questions concerned the cell type composition of early embryonic skin, and the emergence of transcriptional heterogeneity among epithelial and stromal precursor cells. Cells were ...
ORGANISM(S): Mus musculus 
2023-07-16 | E-MTAB-11920 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica trophozoites in mid-logarithmic growth
Entamoeba histolytica is a protozoan parasite which causes colitis and liver abscesses. Using a genomic DNA microarray consisting of 1.6 - 2.0 kb genomic inserts we have generated a transcriptional profile of 1,971 unique parasite transcripts. The 12 arrays in this experiment set were used to esti...
ORGANISM(S): Entamoeba histolytica 
2005-07-06 | E-SMDB-3205 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica plus Caco2 cells
Entamoeba histolytica is a protozoan parasite which causes colitis and liver abscesses. Using a genomic DNA microarray consisting of 1.6 - 2.0 kb genomic inserts we have generated a transcriptional profile of 1,971 unique parasite transcripts. The arrays in this experiment set were used to examine...
ORGANISM(S): Entamoeba histolytica 
2005-07-06 | E-SMDB-3208 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Entamoeba histolytica trophozoites heat shock experiments
Entamoeba histolytica is a protozoan parasite which causes colitis and liver abscesses. A pilot microarray consisting of 360 unique parasite genes was constructed using identical methods to the larger array (1,971 unique genes). The four arrays in this data set were used to ascertain whether the m...
ORGANISM(S): Entamoeba histolytica 
2005-07-06 | E-SMDB-3207 | biostudies-arrayexpress
no omics definedA coordintate global control over cellular transcription
Although much is known about the regulation of eukaryotic transcription, the global controls which determine rates of total transcription within a cell are not well understood. We have investigated the effects that the DNA to protein ratio has on both total cellular transcription and the transcripti...
ORGANISM(S): Schizosaccharomyces pombe 
2011-09-23 | E-TABM-1075 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
RNA sequencing was performed on sorted populations of Lgr6-positive and Lgr6-negative keratinocytes from the interfollicular epidermis and the hair follicle/sebaceous gland, in order to determine the compartment-specific expression signatures of Lgr6+ progenitor cells.
ORGANISM(S): Mus musculus 
2015-10-22 | E-MTAB-3533 | biostudies-arrayexpress
TranscriptomicsmicroRNA Expression in HCC Tissues and Cells
Cell Lines, Cultures and HCC Tumor Tissues.
Malignant and non-malignant hepatocyte cell lines were obtained from the American Type Culture Collection (Manassas, VA) and cultured as recommended by the supplier. Total RNA from three paires of normal human liver tissue and from hepatocellular car...
ORGANISM(S): Homo sapiens 
2011-08-03 | E-MEXP-1125 | biostudies-arrayexpress
TranscriptomicsSub-adult RDX Exposure, Whole Body Tissue Investigation
We investigated ecotoxicological effects and toxicogenomic responses in fathead minnows (Pimephales promelas) exposed to an environmentally-relevant concentration (0.83 mg/L) of the munitions compound cyclotrimethylenetrinitramine (RDX) in one year and multi-generational assays. In the one year ass...
ORGANISM(S): Pimephales promelas 
2010-07-30 | E-GEOD-21102 | biostudies-arrayexpress
TranscriptomicsOne Year RDX Exposure, Liver Tissue Investigation
We investigated ecotoxicological effects and toxicogenomic responses in fathead minnows (Pimephales promelas) exposed to an environmentally-relevant concentration (0.83 mg/L) of the munitions compound cyclotrimethylenetrinitramine (RDX) in one year and multi-generational assays. In the one year ass...
ORGANISM(S): Pimephales promelas 
2010-07-30 | E-GEOD-21100 | biostudies-arrayexpress
Proteomics,MultiomicsPlasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) affects 25% of the population and can progress to cirrhosis, where treatment options are limited. As the liver secrets most of the blood plasma proteins, its diseases should affect the plasma proteome. Plasma Proteome Profiling of 48 patients with cirrhosis ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000084332 | MassIVE
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