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MetabolomicsA pathogen-specific isotope tracing approach reveals metabolic activities and fluxes of intracellular Salmonella

Pathogenic bacteria proliferating inside mammalian host cells need to rapidly adapt to the intracellular environment. How they achieve this and scavenge essential nutrients from the host has been an open question due to the difficulties in distinguishing between bacterial and host metabolites

2023-08-02 | MTBLS1275 | MetaboLights
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
UnknownVascular architecture-on-chip: engineering complex blood vessels for reproducing physiological and heterogeneous hemodynamics and endothelial function.
Not available
S-EPMC11895859 | biostudies-literature
TranscriptomicsA high resolution map of a cyanobacterial transcriptome
Previous molecular and mechanistic studies have identified several principles of prokaryotic transcription, but less is known about the global transcriptional architecture of bacterial genomes. Here we perform a comprehensive study of a cyanobacterial transcriptome, that of Synechococcus elongatus P...
ORGANISM(S): Synechococcus elongatus PCC 7942 
2011-05-16 | E-GEOD-29264 | biostudies-arrayexpress
UnknownSuccess stories: exploring perceptions of former fellows of a global faculty development program for health professions educators.
Not available
S-EPMC11443623 | biostudies-literature
UnknownIntracellular calcium dynamics of lymphatic endothelial and muscle cells co-cultured in a Lymphangion-Chip under pulsatile flow.
Not available
S-EPMC9512566 | biostudies-literature
UnknownMechanotransduction-on-chip: vessel-chip model of endothelial YAP mechanobiology reveals matrix stiffness impedes shear response.
Not available
S-EPMC9761985 | biostudies-literature
TranscriptomicsArray-based comparative genomic hybridization analysis of primary neuroblastoma
We conducted microarray-based comparative genomic hybridization (array-CGH) with a DNA chip carrying 2,464 BAC clones to examine genomic aberrations of 236 neuroblastomas (112 sporadic and 124 mass screening-detected). In paralell, gene-expression profiling was also performed by using in-house cDNA ...
ORGANISM(S): Homo sapiens 
2007-08-06 | E-GEOD-5784 | biostudies-arrayexpress
ModelsSiddhartha2002 - Kinetic modelling of cancer therapies
Siddhartha Jain. Kinetic model for designing a cancer therapy. Cancer Cell International 2, 1 (2002). A kinetic model has been developed to study cancer growth. Cancer growth has been considered as interaction between various independent but interacting compartments. The model considers cell growth...
2024-09-02 | BIOMD0000001048 | BioModels
UnknownManagement of a patient with mantle cell lymphoma who developed severe neurotoxicity after chimeric antigen receptor T-cell therapy in ZUMA-2.
Not available
S-EPMC7570235 | biostudies-literature
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