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MetabolomicsPhospholipid acyl chain diversity controls the tissue-specific assembly of mitochondrial cardiolipins

Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its side chain configurations are tissue-specific, functionally important and generated via post-biosynthetic remodeling. However, this process lacks the necessary specificit...

2020-05-22 | MTBLS1446 | MetaboLights
TranscriptomicsPrenatal stress-induced programming of genome-wide promoter DNA methylation in 5-Htt deficient mice
The serotonin transporter (5-HTT) gene-linked polymorphic region has been suggested to play a modulatory role in mediating the effects of early-life stress on psychopathology rendering carriers of the low-expression short (s)-allele more vulnerable to environmental adversity in later life. Here we a...
ORGANISM(S): Mus musculus 
2014-11-18 | E-GEOD-51634 | biostudies-arrayexpress
TranscriptomicsSex-specific effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene x environment interactions
prenatal stress response, genetic modification Background: Prenatal stress (PS) exposure has been shown to increase the risk for emotional disorders in later life. Furthermore, the serotonin transporter (5-HTT) genotype is suggested to exert a modulating effect on the association between early life ...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-26025 | biostudies-arrayexpress
UnknownQuantifying prion disease penetrance using large population control cohorts.
Not available
S-EPMC4774245 | biostudies-literature
UnknownLow-dose hydrocortisone in patients with COVID-19 and severe hypoxia: The COVID STEROID randomised, placebo-controlled trial.
Not available
S-EPMC8441888 | biostudies-literature
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