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TranscriptomicsTranscription profiling of human HEK293 cells transfected with either wild type or delta exon 4 mutants of surfacant protein C
Mutations in the gene encoding surfactant protein C (SFTPC) have been linked to interstitial lung disease in children and adults. Expression of the index mutation, SP-Cdeltaexon4, in transiently transfected cells and type II cells of transgenic mice resulted in misfolding of the proprotein, activat...
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-2980 | biostudies-arrayexpress
GenomicsMus musculus strain:BALB/c
Mus musculus strain:BALB/c Metagenome
PRJNA1274167 | ENA
TranscriptomicsDefining the Roles and Regulation of the GATA-factor ELT-2 in the C. elegans Endoderm
We identified genome-wide sites of occupancy for the intestine-specific transcription factor ELT-2 in L3-staged N2 worm by performing ELT-2 ChIP-seq on whole worms; we performed RNA-seq on L3-staged N2 whole worms To identify DNA regions of direct ELT-2 occupancy, we performed the following ChIP-seq...
ORGANISM(S): Caenorhabditis elegans 
2016-03-30 | E-GEOD-71720 | biostudies-arrayexpress
GenomicsMus musculus strain:BALB/c
Mus musculus strain:BALB/c Raw sequence reads
PRJNA1271270 | ENA
ProteomicsExpression of a surfactant protein C mutation impairs postnatal expansion of alveolar type 2 epithelial cells leading to permanent cell loss and decreased repair capacity in adult lungs
Mutations in the gene encoding surfactant protein C (SFTPC) are associated with interstitial lung disease in children and adults. To assess the natural history of disease, we knocked-in a familial, disease-associated SFTPC mutation, L188Q (L184Q in mice), into the mouse Sftpc locus. Expression of th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-08-19 | MSV000085976 | MassIVE
TranscriptomicsHost and pathogen interaction: time course [C. albicans]
The interaction between fungal pathogen and host during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histological analysis of surviving fis...
ORGANISM(S): Candida albicans 
2013-08-26 | E-GEOD-32117 | biostudies-arrayexpress
ProteomicsProtein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice
Total and phosphoproteomic analysis of liver and white adipose tissue from mice with specific deletion of protein kinase C epsilon in AgRP nerons of the hypothalamus, 30 min after i.p. injection with glucose.
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD065137 | Pride
Glucose agrp neuron hypothalamus protein kinase c epsilon 
MetabolomicsLC-MS analysis of faecal extracts obtained during colorectal cancer resectional surgery

A prospective observational pilot study from right-sided colorectal cancer (RCRC) patients was performed at Imperial College London NHS Trust, UK. Treatment naïve patients undergoing elective resectional surgery for primary RCRCs were recruited. Fresh intra-luminal fecal samples were obtained at ...

2025-07-11 | MTBLS11775 | MetaboLights
ProteomicsPhotoredox-catalyzed decarboxylative C-terminal differentiation for bulk and single molecule proteomics
Methods for the selective labeling of functional groups on peptides are being developed and used in the workflow of both current and emerging proteomics technologies, such as single-molecule fluorosequencing. Photoredox methods in discriminative targeting of the terminal carboxylic acid from the int...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2021-06-01 | MSV000087551 | MassIVE
ProteomicsThe Effect of Temperature Conditioning (9°C and 20°C) on the Proteome of Steinernema carpocapsae and Heterorhabditis megidis Infective Juveniles
Entomopathogenic nematodes (Rhabditida; Steinernematidae and Heterorhabditidae) are insect parasites which are of economic importance due to their use as biocontrol agents. The third larval stage, infective juveniles (IJs) leave the natal host and move in the soil to locate a new insect host. Both f...
ORGANISM(S): Heterorhabditis megidis Escherichia coli Steinernema carpocapsae 
2022-03-27 | PXD027608 | Pride
Enomopathogenic nematodes Steinernema carpocapsae Heterorhabditis megidis Temperature conditioning 
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