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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
GenomicsChIP-seq experiment to determine the genomic binding sites of mutant V5-tagged ZFHX2 R1913K protein in a stable-expressing human SH-SY5Y neuroblastoma cell line
A novel missense mutation has been identified in a human pain-insensitive family in the gene ZFHX2. We modelled this mutation in mice by changing the orthologous amino acid and carried out pain behaviour tests in mutant BAC transgenic mice. These showed a phenotype of hyposensitivity to noxious ther...
ORGANISM(S): Homo sapiens 
2018-06-11 | E-MTAB-5651 | biostudies-arrayexpress
TranscriptomicsMicroarray of BAC transgenic Zfhx2 p.R1907K mutant mice (4 genomic copies) versus wild-types
A novel missense mutation has been identified in a human pain-insensitive family in the gene ZFHX2. We modelled this mutation in mice by changing the orthologous amino acid and carried out pain behaviour tests in mutant BAC transgenic mice. These showed a phenotype of hyposensitivity to noxious ther...
ORGANISM(S): Mus musculus 
2018-06-11 | E-MTAB-5650 | biostudies-arrayexpress
UnknownUsing the theoretical domains framework to determine the barriers and facilitators to medication adherence in Parkinson's disease.
Not available
S-EPMC10423922 | biostudies-literature
TranscriptomicsWhole blood mRNA transcription profiling of host immune changes in neonatal sepsis during vancomycin therapy
The purpose of this study was to investigate changes in host gene expression profiles of neonatal infants with sepsis prior to the initiation of and during vancomycin therapy, to identify treatment-responsive genes and signature pathways associated with recovery from neonatal sepsis. The study analy...
ORGANISM(S): Homo sapiens 
2025-11-25 | E-MTAB-15687 | biostudies-arrayexpress
UnknownMedullary Tegmental Cap Dysplasia: Fetal and Postnatal Presentations of a Unique Brainstem Malformation.
Not available
S-EPMC10187821 | biostudies-literature
GenomicsEscherichia coli E22
Enteropathogenic Escherichia coli
PRJNA15577 | ENA
UnknownPiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomes.
Not available
S-EPMC4161314 | biostudies-literature
UnknownUsing Technology-Supported Transfer of Care Systems: Informing Good Practice Recommendations.
Not available
S-EPMC8005999 | biostudies-literature
TranscriptomicsTranscription profiling of human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis
Human growth plate chondrocytes were isolated from the distal femoral growth plate from 3 different adolescents undergoing epiphysiodesis. Cell were isolated and grown in monolayers, long term, in 20% serum. Cells were replated and cultured 48 h in 0.5% serum.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1278 | biostudies-arrayexpress
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