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TranscriptomicsGenome wide gene expression profiles of Drosophila l(3)mbt larval brains and cultured tumors
Mutants in the Drosophila gene lethal (3) malignant brain tumor cause malignant growth in the larval brain. This data shows the changes in gene expression profile associated to mutations in l(3)mbt, both in situ in third instar larval brains and in tumors cultured for 1 5 and 10 (T1, T5, T10) rounds...
ORGANISM(S): Drosophila melanogaster 
2011-02-01 | E-GEOD-24917 | biostudies-arrayexpress
ProteomicsThe TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability
Background: TP53, the most frequently mutated gene in human cancers, orchestrates a complex transcriptional program crucial for cancer prevention. While certain TP53-dependent genes have been extensively studied, others, like the recently identified RNF144B, remained poorly understood. This E3 ubiqu...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-23 | PXD051459 | Pride
Tumor suppressor Genomic instability Cancer Aneuploidy 
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