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Primary mitochondrial disease (PMD) patients manifesting cardiomyopathy are twice as likely to die as other PMD patients. One PMD with cardiomyopathy is caused by null mutations in the heart-muscle isoform of the adenine nucleotide translocator (ANT1) gene, the severity of the cardiomyopathy being m...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-28 | PXD058090 | Pride
Supplemental NAD+ precursors show metabolic and functional benefits in rodent models of disease and are being explored as potential therapeutics in human studies. However, the wide range of processes that involve NAD+ in every cell and subcellular compartment make it difficult to narrow down mechani...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-08-15 | MSV000098839 | MassIVE
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