Sort   by:  
 Page size 
MetabolomicsSarcosine decreases in sarcopenia and enhances muscle regeneration and adipose thermogenesis by activating ant-inflammatory macrophages (cohort1)

Age-related changes in circulating metabolites significantly influence systemic physiology and may contribute to diseases like sarcopenia. Although metabolic dysregulation is closely linked to sarcopenia, the roles of specific metabolites remain unclear. Here we performed comprehensive plasma met...

2025-05-06 | MTBLS12015 | MetaboLights
ProteomicsAAV-mediated transduction of the Ant1 gene restores heart function in the Ant1-/- mouse model of mitochondrial cardiomyopathy
Primary mitochondrial disease (PMD) patients manifesting cardiomyopathy are twice as likely to die as other PMD patients. One PMD with cardiomyopathy is caused by null mutations in the heart-muscle isoform of the adenine nucleotide translocator (ANT1) gene, the severity of the cardiomyopathy being m...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-28 | PXD058090 | Pride
Mitochondria Mouse Ant1 Heart 
GenomicsRole of ANT1 in pulmonary fibrosis
Role of ANT1 in pulmonary fibrosis
PRJNA1022157 | ENA
TranscriptomicsRole of ANT1 in pulmonary fibrosis
Crispr KO of ANT1 in Beas2b cells versus control cells were treated with media or bleomycin
ORGANISM(S): Homo sapiens 
2023-10-03 | GSE244305 | GEO
TranscriptomicsAdenine Nucleotide translocase 1 (ANT1) Deficiency Impairs Macrophage Metabolism and Migration, Protecting Against Emphysema in COPD
Macrophage-mediated inflammation drives various lung diseases, including chronic obstructive pulmonary disease (COPD). COPD macrophages have dysfunctional mitochondrial metabolism and function which lead to a chronic inflammatory lung environment. However, the factors regulating this altered metabol...
ORGANISM(S): Mus musculus 
2025-03-31 | GSE287944 | GEO
GenomicsAdenine Nucleotide translocase 1 (ANT1) Deficiency Impairs Macrophage Metabolism and Migration, Protecting Against Emphysema in COPD
Adenine Nucleotide translocase 1 (ANT1) Deficiency Impairs Macrophage Metabolism and Migration, Protecting Against Emphysema in COPD
PRJNA1215335 | ENA
TranscriptomicsAdenine Nucleotide translocase 1 (ANT1) Deficiency Impairs Macrophage Metabolism and Migration, Protecting Against Emphysema in COPD [6 months]
Macrophage-mediated inflammation drives various lung diseases, including chronic obstructive pulmonary disease (COPD). COPD macrophages have dysfunctional mitochondrial metabolism and function which lead to a chronic inflammatory lung environment. However, the factors regulating this altered metabol...
ORGANISM(S): Mus musculus 
2025-03-31 | GSE289559 | GEO
UnknownANT1 overexpression models: Some similarities with facioscapulohumeral muscular dystrophy.
Not available
S-EPMC9434167 | biostudies-literature
UnknownPartial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1<sup>-/-</sup> plus mtDNA mutant mice.
Not available
S-EPMC12800341 | biostudies-literature
TranscriptomicsPartial phenotypic rescue of the Sesb1 mitochondrial ANT1 disease model in Drosophila
Study of gene expression patterns of Drosophila melanogaster Sesb1 mutants compared to wild type Inbreeding under stressful conditions inevitably results in the selection of compensatory alleles of many genes. In order to avoid such issues, and thus determine the global effects on gene expression of...
ORGANISM(S): Drosophila melanogaster 
2014-08-11 | E-GEOD-55187 | biostudies-arrayexpress
Sort   by:  
 Page size