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ProteomicsRetinal proteomics of a mouse model of dystroglycanopathies shows changes in different photoreceptor regions
Mutations in the POMT1 gene, encoding a protein O-mannosyltransferase essential for alpha-dystroglycan (α-DG) glycosylation, are frequently observed in a group of rare congenital muscular dystrophies, collectively known as dystroglycanopathies. However, it is hitherto unclear whether the effects se...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-10 | PXD023704 | Pride
Mouse model Dystroglycanopathies Photoreceptor 
ProteomicsOxonium ion guided analysis of quantitative proteomics data reveals site-specific O-glycosylation of anterior gradient protein 2 (AGR2)
Developments in mass spectrometry (MS)-based analyses of glycoproteins have been important to study changes in glycosylation related to disease. Recently, the characteristic pattern of oxonium ions in glycopeptide fragmentation spectra had been used to assign different sets of glycopeptides. In part...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025805 | Pride
Glycoproteomics  tmt labeling  oxonium ion  lc−ms/ms  o-glycosylation  colorectal cancer  agr2 
ProteomicsN-glycoproteins have a major role in MGL binding to colorectal cancer cell lines
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide due in part to a high proportion of patients diagnosed at advanced stages of the disease. For this reason, many efforts have been made towards new approaches for early detection and prognosis. Cancer-associated aberrant gl...
ORGANISM(S): Homo sapiens (Human) 
2020-08-10 | PXD020344 | Pride
Glycoproteomics  tmt labelling  c-type lectin  colorectal cancer  lacdinac  tn antigen 
UnknownSARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
Not available
S-EPMC11117088 | biostudies-literature
UnknownRisk of COVID-19 after natural infection or vaccination.
Not available
S-EPMC10518569 | biostudies-literature
UnknownGenetic Loci Associated With Periodontitis: The FinnGen Study Based on National Health Registers.
Not available
S-EPMC12377943 | biostudies-literature
UnknownClinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials.
Not available
S-EPMC10346130 | biostudies-literature
UnknownDrosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Not available
S-EPMC4426361 | biostudies-literature
UnknownCross-Sectional Study on MRI Restaging After Chemoradiotherapy and Interval to Surgery in Rectal Cancer: Influence on Short- and Long-Term Outcomes.
Not available
S-EPMC6341052 | biostudies-literature
UnknownAbandonment of Routine Radiotherapy for Nonlocally Advanced Rectal Cancer and Oncological Outcomes.
Not available
S-EPMC10739079 | biostudies-literature
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